Borylative Cyclization of 1,6-Allenynes Driven by BCl3

被引：6

作者：

Yang, Chun-Hua ^{[1
]}

Sun, Xiangkun ^{[1
]}

Niu, Congcong ^{[1
]}

Zhang, Zhiwei ^{[1
]}

Liu, Mingzhu ^{[1
]}

Zheng, Fangjie ^{[1
]}

Jiang, Ling ^{[2
]}

Kong, Xiangtao ^{[1
]}

Yang, Zhantao ^{[1
]}

机构：

[1] Anyang Normal Univ, Coll Chem & Chem Engn, Henan Key Lab New Optoelect Funct Mat, Anyang 455000, Peoples R China

[2] Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China

来源：

ORGANIC LETTERS | 2021年 / 23卷 / 20期

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

ALDER ENE REACTION; CATALYZED CYCLOISOMERIZATION; CARBOCYCLIZATION; CYCLOADDITION; ACTIVATION; ALLENYNES; ALKYNES; DIYNES;

D O I：

10.1021/acs.orglett.1c03062

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A metal-free intramolecular borylative cyclization of 1,6-allenynes driven by BCl3 was developed. This method provides a general and practical strategy to construct valuable pyrrolidines containing all-carbon quaternary centers or 3,5-dihydroazepine derivatives depending on the substituents of the allene, with conjugative and sterically hindered phenyl groups favoring the latter.

引用

页码：8050 / 8055

页数：6

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