The Kinetics of Neutrophils in Photodynamic Theraphy as Anti-Tumor

被引:0
作者
Amalina, M. A. [1 ]
Zulaziz, Natasha [1 ]
Ho, Cassandra [1 ]
Azhim, Azran [1 ]
Miyazaki, Hiromi [2 ]
Saito, Daizoh [2 ]
Kinoshita, Manabu [3 ]
Horiuchi, Toshikatsu [4 ]
Himeno, Naomi [5 ]
Shinomiya, Nariyoshi [6 ]
Morimoto, Yuji [6 ]
机构
[1] Univ Teknol Malaysia, Malaysia Japan Inst Technol, Kuala Lumpur, Malaysia
[2] Natl Def Med Coll, Div Traumatol, Tokorozawa, Saitama, Japan
[3] Natl Def Med Coll, Dept Immunol & Microbiol, Tokorozawa, Saitama, Japan
[4] Natl Def Med Coll, Dept Internal Med, Div Hematol, Tokorozawa, Saitama, Japan
[5] iCAT Corp, Osaka, Japan
[6] Natl Def Med Coll, Dept Integrat Physiol & Bionano Med, Tokorozawa, Saitama, Japan
来源
2015 10TH ASIAN CONTROL CONFERENCE (ASCC) | 2015年
关键词
photodynamic therapy; neutrophil; fluorescence; anti-tumor; Photofrin;
D O I
暂无
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Photodynamic therapy (PDT) is known for its antitumor property. PDT uses a photosensitizer combined with light to kill cancer cells. Different to other non-surgical cancer treatments such as chemotherapy and radiotherapy which suppress immune system, it is suggested that PDT promotes an accumulation of neutrophils causing destruction of tumor cells; however, this is not be fully elucidated. Neutrophils is known to be a main player in the innate immunity and is closely related to the inflammation of the tumor site after PDT. Therefore, in this research, we investigated the relationship of neutrophils kinetics and anti-tumor property of PDT.
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页数:4
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