Effects of Artemisia pallens Wall on blood glucose levels in normal and alloxan-induced diabetic rats

被引:88
|
作者
Subramoniam, A [1 ]
Pushpangadan, P [1 ]
Rajasekharan, S [1 ]
Evans, DA [1 ]
Latha, PG [1 ]
Valsaraj, R [1 ]
机构
[1] TROP BOT GARDEN & RES INST,DIV ETHNOMED,THIRUVANANTHAPURAM 695562,KERALA,INDIA
关键词
Artemisia pallens; diabetes; glucose; anti-hyperglycaemic; alloxan;
D O I
10.1016/0378-8741(95)01329-6
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Oral administration of the methanol extract of the aerial parts of Artemisia pallens Wall. (used in Indian folk medicine for the treatment of diabetes mellitus) led to significant blood glucose lowering effect in glucose-fed hyperglycaemic and alloxan-induced diabetic rats. This effect of the extract was dose dependent and significant at 100 mg/kg level in glucose-fed rats. In fasted normal rats, the extract caused a moderate hypoglycaemic effect at a higher dose (1000 mg/kg). The water extract (1000 mg/kg) was inactive.
引用
收藏
页码:13 / 17
页数:5
相关论文
共 50 条
  • [21] Hypoglicemic effect of Leandra lacunosa in normal and alloxan-induced diabetic rats
    Cunha, W. R.
    Arantes, G. M.
    Ferreira, D. S.
    Lucarini, R.
    Silva, M. L. A.
    Furtado, N. A. J. C.
    da Silva Filho, A. A.
    Crotti, A. E. M.
    Araujo, A. R. B.
    FITOTERAPIA, 2008, 79 (05) : 356 - 360
  • [22] AMELIORATIVE EFFECTS OF Alpinia calcarata IN ALLOXAN-INDUCED DIABETIC RATS
    Raj, Navin
    Nadeem, Sayyed
    Jain, Samir
    Raj, Chanchal
    Nandi, Kuldeep Chouhan Prithwish
    DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES, 2011, 6 (03) : 991 - 997
  • [23] Effect of aqueous extract of Cyamopsis tetragonoloba Linn. beans on blood glucose level in normal and alloxan-induced diabetic rats
    Mukhtar, Hayat M.
    Ansari, S.H.
    Ali, M.
    Bhat, Z.A.
    Naved, T.
    Indian Journal of Experimental Biology, 2004, 42 (12) : 1212 - 1215
  • [24] Palm oil and ground nut oil supplementation effects on blood glucose and antioxidant status in alloxan-induced diabetic rats
    Adewale, Olabiyi Folorunso
    Isaac, Olatunji Olusola
    Tunmise, Makinwa Temitope
    Omoniyi, Oguntibeju Oluwafemi
    PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 29 (01) : 83 - 87
  • [25] Antioxidant Effect of Dietary Supplement Withania somnifera L. Reduce Blood Glucose Levels in Alloxan-Induced Diabetic Rats
    Rajangam Udayakumar
    Sampath Kasthurirengan
    Ayyappan Vasudevan
    Thankaraj Salammal Mariashibu
    Jesudass Joseph Sahaya Rayan
    Chang Won Choi
    Andy Ganapathi
    Sei Chang Kim
    Plant Foods for Human Nutrition, 2010, 65 : 91 - 98
  • [26] Antioxidant Effect of Dietary Supplement Withania somnifera L. Reduce Blood Glucose Levels in Alloxan-Induced Diabetic Rats
    Udayakumar, Rajangam
    Kasthurirengan, Sampath
    Vasudevan, Ayyappan
    Mariashibu, Thankaraj Salammal
    Rayan, Jesudass Joseph Sahaya
    Choi, Chang Won
    Ganapathi, Andy
    Kim, Sei Chang
    PLANT FOODS FOR HUMAN NUTRITION, 2010, 65 (02) : 91 - 98
  • [27] Antidiabetic Effects of Aqueous Infusions of Artemisia herba-alba and Ajuga iva in Alloxan-Induced Diabetic Rats
    Boudjelal, Amel
    Siracusa, Laura
    Henchiri, Cherifa
    Sarri, Madani
    Abderrahim, Benkhaled
    Baali, Faiza
    Ruberto, Giuseppe
    PLANTA MEDICA, 2015, 81 (09) : 696 - 704
  • [28] Hypoglycemic and hypolipidemic effects of aqueous extract of Arachis hypogaea in normal and alloxan-induced diabetic rats
    Bilbis, LS
    Shehu, RA
    Abubakar, AG
    PHYTOMEDICINE, 2002, 9 (06) : 553 - 555
  • [29] Prevention of proliferative changes of forestomach mucosa by blood glucose control with insulin in alloxan-induced diabetic rats
    Sano, Tomoya
    Ozaki, Kiyokazu
    Kodama, Yasushi
    Matsuura, Tetsuro
    Narama, Isao
    CANCER SCIENCE, 2009, 100 (04): : 595 - 600
  • [30] Pentoxifylline response in alloxan-induced diabetic rats
    Satar, Bulent
    Yildiz, Oguzhan
    Karatas, Erkan
    Boydag, Serkan
    Akkaya, Abdullah
    ACTA OTO-LARYNGOLOGICA, 2008, 128 (11) : 1221 - 1226