Platinum on Carbon-Catalyzed Hydrodefluorination of Fluoroarenes using Isopropyl Alcohol-Water-Sodium Carbonate Combination

被引：43

作者：

Sawama, Yoshinari ^{[1
]}

Yabe, Yuki ^{[1
]}

Shigetsura, Masahiro ^{[1
]}

Yamada, Tsuyoshi ^{[1
]}

Nagata, Saori ^{[1
]}

Fujiwara, Yuta ^{[1
]}

Maegawa, Tomohiro ^{[1
]}

Monguchi, Yasunari ^{[1
]}

Sajiki, Hironao ^{[1
]}

机构：

[1] Gifu Pharmaceut Univ, Organ Chem Lab, Gifu 5011196, Japan

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2012年 / 354卷 / 05期

关键词：

chemoselectivity; defluorination; haloarenes; heterogeneous catalysis; platinum; FLUORINE BOND ACTIVATION; C-F ACTIVATION; ROOM-TEMPERATURE; ARYL HALIDES; AROMATIC FLUOROCARBONS; MILD CONDITIONS; REDUCTIVE DEFLUORINATION; TRANSFER HYDROGENATION; DEGRADATION METHOD; CARBENE COMPLEXES;

D O I：

10.1002/adsc.201100927

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

We have developed a platinum on carbon-isopropyl alcohol-catalyzed and widely applicable defluorination method for fluoroarenes, and the addition of water and sodium carbonate efficiently accelerated the reaction. The defluorination readily occurred under the reaction conditions in comparison with the dehalogenation of other aromatic halides (fluorine>chlorine>bromineiodine).

引用

页码：777 / 782

页数：6

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