Composite lymphoma of Hodgkin lymphoma and mycosis fungoides: Previously undescribed in the same extracutaneous site

被引:16
作者
Bee, CS [1 ]
Blaise, YP [1 ]
Dunphy, CH [1 ]
机构
[1] St Louis Univ, Hlth Sci Ctr, Dept Pathol, Div Hematopathol, St Louis, MO 63014 USA
关键词
mycosis fungoides; Hodgkin lymphoma; immunohistochemistry; flow cytometry;
D O I
10.3109/10428190109064615
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Mycosis fungoides (NIF), diagnosed and limited to the skin, has been associated with the subsequent development of Hodgkin lymphoma (HL), most commonly of the nodular sclerosing (NS) subtype. In the previously described cases, there are none in which the extracutaneous tissue was simultaneously involved by HL and residual/relapsing NIF. Here we report a case of HL, mixed cellularity (MC) subtype, arising in an inguinal lymph node in a patient with a previous diagnosis of MR We describe the immunophenotypic, histologic and immunohistochemical findings of a composite lymphoma containing the HL, MC subtype and MT. The importance of detecting NIF in addition to the HL in the extracutaneous site with available diagnostic modalities is highlighted.
引用
收藏
页码:543 / 549
页数:7
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