DIAGNOSTIC ACCURACY OF ULTRASOUND AND 18-F-FDG PET OR PET/CT FOR PATIENTS WITH SUSPECTED RECURRENT PAPILLARY THYROID CARCINOMA

被引:15
作者
Choi, Jin Woo [1 ,2 ,3 ]
Lee, Jeong Hyun [1 ,2 ]
Baek, Jung Hwan [1 ,2 ]
Choi, Byung Se [1 ,2 ]
Jeong, Kyung Soon [1 ,2 ]
Ryu, Jin-Sook [4 ]
Kim, Tae Yong [5 ]
Kim, Won Bae [5 ]
Shong, Young Kee [5 ]
机构
[1] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Radiol, Seoul 138736, South Korea
[2] Univ Ulsan, Coll Med, Asan Med Ctr, Res Inst Radiol, Seoul 138736, South Korea
[3] Konkuk Univ Sch Med, Konkuk Univ Med Ctr, Dept Radiol, Seoul, South Korea
[4] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Nucl Med, Seoul 138736, South Korea
[5] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Internal Med, Seoul 138736, South Korea
关键词
Thyroid cancer; Ultrasound; Positron emission tomography; Recurrence; Metastasis; POSITRON-EMISSION-TOMOGRAPHY; FOLLOW-UP; SERUM THYROGLOBULIN; ULTRASONOGRAPHIC DIFFERENTIATION; POSTOPERATIVE-PATIENTS; NECK ULTRASONOGRAPHY; CERVICAL RECURRENCE; LYMPH-NODES; FDG-PET; CANCER;
D O I
10.1016/j.ultrasmedbio.2010.07.013
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The purpose of this study was to evaluate the diagnostic accuracies of ultrasound (US) and 18-F-FDG positron emission tomography (PET) or PET/computed tomography (CT) for detecting recurrent papillary thyroid carcinoma (PTC) after total thyroidectomy. Our study enrolled 76 postoperative patients who underwent both neck US and PET because of the suspicion of recurrence. The results of US and PET were correlated with the histopathology, the radioactive iodine whole body scan (WBS) or the clinical follow-up results. Among them, 53 patients had recurrent disease (local recurrence, 42; distant metastasis, 3; elevated Tg level, 8) and 23 showed no evidence of disease. From the analysis, US showed higher diagnostic accuracy, sensitivity and specificity compared with those of PET (71.1%, 71.7% and 69.6% vs. 55.3%, 56.6%, and 52.2%). PET added diagnostic information in a limited number of patients with negative results on neck US (3 with neck recurrence and 2 with distant metastasis). (E-mail: jeonghlee@hanmir.com) (C) 2010 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码:1608 / 1615
页数:8
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