Laser ablation of posterior nasal nerves for rhinitis

被引:21
作者
Krespi, Yosef P. [1 ]
Wilson, Karen A. [1 ]
Kizhner, Victor [2 ]
机构
[1] Lenox Hill Hosp Northwell Hlth, 100 E 77th S4, New York, NY 10075 USA
[2] Mt Sinai St Lukes, 1111 Amsterdam Ave, New York, NY 10025 USA
关键词
DENERVATION; MUCOSA;
D O I
10.1016/j.amjoto.2020.102396
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background: Posterior nasal nerve (PNN) surgery, Radiofrequency (RF), and cryoablation have been described as alternative treatments for allergic and vasomotor rhinitis. We hypothesize that endoscopic (diode) laser ablation (ELA) is effective and less invasive than previously described methods. Methods: An IRB approved prospective study was performed. Thirty-two patients with chronic rhinitis and nasal congestion resistant to medical management were recruited. Total Nasal Symptom Score (TNSS) measurements were used to assess symptom severity and treatment outcomes. ELA was performed bilaterally in the clinic with a 940 nm diode laser with CW 5 W output, under topical/local anesthesia in 21 patients, while the remaining 11 were treated under sedation in the operating room. The 400-micron uninitiated diode laser fiber tip with a malleable protective shaft was specially designed for PNN ablation. The fiber was pre-shaped according to the intranasal anatomy and endoscopically advanced toward the posterior middle meatus. Patients were followed up for the first 90 days after treatment. Results: ELA was successfully completed in 97% of patients. No crusting, epistaxis, or other complications were observed. One patient could not be treated in the office due to limited endoscopic access. TNSS was reduced significantly after30 and 90 days (mean +/- SD: 6.0 +/- 0.7 prior to ablation, 2.3 +/- 0.4 at 90 days, p < .001). Rhinitis and congestion scores decreased at 30 and 90 days after treatment compared to the baseline (p < .001). Conclusion: ELA of the PNN region is safe and well tolerated both in the office and ambulatory settings. Symptom scores were significantly decreased after 30 and 90 days. This new minimally invasive method appears to be a promising treatment method.
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相关论文
共 11 条
[1]   Histological Changes Occurring After Endoluminal Ablation With Two Diode Lasers (940 and 1319 nm) From Acute Changes to 4 Months [J].
Bush, Ronald G. ;
Shamma, H. Nicholas ;
Hammond, Karin .
LASERS IN SURGERY AND MEDICINE, 2008, 40 (10) :676-679
[2]   Endovenous laser ablation: an experimental study on the mechanism of action [J].
Disselhoff, B. C. V. M. ;
Rem, A. I. ;
Verdaasdonk, R. M. ;
Kinderen, D. J. Der ;
Moll, F. L. .
PHLEBOLOGY, 2008, 23 (02) :69-76
[3]   A New Method of Identifying the Posterior Inferior Nasal Nerve: Implications for Posterior Nasal Neurectomy [J].
Eren, Erdem ;
Zeybek, Gulsah ;
Ecevit, Cenk ;
Arslanoglu, Secil ;
Ergur, Ipek ;
Kiray, Amac .
JOURNAL OF CRANIOFACIAL SURGERY, 2015, 26 (03) :930-932
[4]   Surgical management of vasomotor rhinitis: A systematic review [J].
Halderman, Ashleigh ;
Sindwani, Raj .
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 2015, 29 (02) :128-134
[5]   Cryosurgical posterior nasal tissue ablation for the treatment of rhinitis [J].
Hwang, Peter H. ;
Lin, Bryant ;
Weiss, Raymond ;
Atkins, James ;
Johnson, Jacob .
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2017, 7 (10) :952-956
[6]   Cryotherapy for the Treatment of Chronic Rhinitis: A Qualitative Systematic Review [J].
Kompelli, Anvesh R. ;
Janz, Tyler A. ;
Rowan, Nicholas R. ;
Nguyen, Shaun A. ;
Soler, Zachary M. .
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 2018, 32 (06) :491-501
[7]  
Lalwani AK., 2012, Current Diagnosis and Treatment in Otolaryngology Head and Neck Surgery, V3rd
[8]   Prolonged denervation induces remodeling of nasal mucosa in rat model of posterior nasal neurectomy [J].
Nishijima, Hironobu ;
Kondo, Kenji ;
Toma-Hirano, Makiko ;
Kikuta, Shu ;
Ando, Mizuo ;
Ueha, Rumi ;
Yamasoba, Tatsuya .
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2017, 7 (07) :670-678
[9]   Denervation of nasal mucosa induced by posterior nasal neurectomy suppresses nasal secretion, not hypersensitivity, in an allergic rhinitis rat model [J].
Nishijima, Hironobu ;
Kondo, Kenji ;
Toma-Hirano, Makiko ;
Iwasaki, Shinichi ;
Kikuta, Shu ;
Fujimoto, Chisato ;
Ueha, Rumi ;
Kagoya, Ryoji ;
Yamasoba, Tatsuya .
LABORATORY INVESTIGATION, 2016, 96 (09) :981-993
[10]   Magnetic Resonance-Guided Laser Induced Thermal Therapy for Glioblastoma Multiforme: A Review [J].
Norred, Sarah E. ;
Johnson, Jacqueline Anne .
BIOMED RESEARCH INTERNATIONAL, 2014, 2014