Receptors, rafts, and microvesicles in thrombosis and inflammation

被引:54
作者
López, JA [1 ]
Del Conde, I [1 ]
Shrimpton, CN [1 ]
机构
[1] Baylor Coll Med, Thrombosis Res Sect, Houston, TX 77030 USA
关键词
hemostasis; lipid rafts; membrane microdomains;
D O I
10.1111/j.1538-7836.2005.01463.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hemostasis at sites of blood vessel injury and its pathologic counterpart, thrombosis, involve a complex interplay between several blood elements: soluble proteins of the blood coagulation system, blood cells (most prominently platelets) and cell fragments, and elements of the vessel wall (endothelial cells and, at sites of injury, the exposed matrix and deeper cellular components). In this review, we focus on ways in which specialized membrane microdomains known as lipid rafts are involved in various phases of hemostasis and thrombosis.
引用
收藏
页码:1737 / 1744
页数:8
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