A Review on Versatile Eco-Friendly Applications of Microbial Proteases in Biomedical and Industrial Applications

Enzymes are the keystone for metabolism or the chemical reactions in biological systems. They help to build certain substances and break others down. Enzymes play a critical role in our bodies, industries and corporate sectors. Protease is an enzyme that helps break the peptide bonds present in the protein and separates the amino acids. Microbial proteases are the ones where the bacteria can produce the protease enzyme. Among many industrial enzymes, microbial protease has a versatile role in many fields like laundry, leather preparation, feather degradation, detergent preparation, biocontrol agents, optical lens cleaners, tannery, deproteinization of prawn shell, prevention of putrefaction of cutting oil, food preservatives, chelating agents, fodder additives, removal and degradation of polymeric substances (EPS), removal of hairs in buffalo hide, waste treatment, bioremediation process, reduction of waste-activated sludge and biofilm formation, degumming of silk, cosmetics (to remove glabellar-frown lines), cheese making, Meat tenderization, rehydration of goat skins and reduced water quantity, fibrin degradation, photographic, silver recovery from X-ray films, dairy industry, control harmful nematodes, fruit juice, and bakery, soybean paste, and sauce industry, pulp mills, alcohol production, fish processing wastes, prion degradation. Microbial protease is popularly used in the detergent industry, leather industry, textile industry, food industry, dairy industry, meat processing industry, bakery industry, pharmaceutical industry, etc.