Short communication:: Apoptosis regulates passive immune transfer in newborn kids

被引：33

作者：

Castro-Alonso, A. ^{[3
]}

Castro, N. ^{[1
]}

Capote, J. ^{[2
]}

Morales-delaNuez, A. ^{[1
]}

Moreno-Indias, I. ^{[1
]}

Sanchez-Macias, D. ^{[1
]}

Herraez, P. ^{[3
]}

Arguello, A. ^{[1
]}

机构：

[1] Las Palmas Gran Canaria Univ, Dept Anim Sci, Arucas 35413, Spain

[2] Canary Agron Sci Inst, Tenerife 38200, Spain

[3] Las Palmas Gran Canaria Univ, Dept Morphol, Arucas 35413, Spain

来源：

JOURNAL OF DAIRY SCIENCE | 2008年 / 91卷 / 05期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

apoptosis; enterocyte; immune passive transfer; immunoglobulin G;

D O I：

10.3168/jds.2007-0814

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Ten newborn kids were used to evaluate the relationship between apoptosis and passive immune transfer in neonatal enterocytes. Kids were slaughtered in groups of 2 at birth, 1, 2, 3, or 60 d postpartum, and samples of duodenal epithelium collected from each animal. Samples were fixed, dehydrated, and embedded in paraffin wax. Sections were assessed for apoptotic cells and immunostained for IgG. Our results suggest that IgG absorption is mediated by apoptotic enterocytes. Thus, delaying apoptosis may improve the success of passive immune transfer.

引用

页码：2086 / 2088

页数：3

共 8 条

[1] Growth of milk replacer kids fed under three different managements [J].

Argüello, A ;

Castro, N ;

Capote, J .

JOURNAL OF APPLIED ANIMAL RESEARCH, 2004, 25 (01) :37-40

[2]

BIERNAT M, 2003, P 9 INT S DIG PHYS P, P46

[3] Short communication:: Addition of milk replacer to colostrum whey:: Effect on immunoglobulin G passive transfer in Majorera kids [J].

Castro, N. ;

Capote, J. ;

Morales, L. ;

Quesada, E. ;

Briggs, H. ;

Argullo, A. .

JOURNAL OF DAIRY SCIENCE, 2007, 90 (05) :2347-2349

[4] Effects of lyophilized colostrum and different colostrum feeding regimens on passive transfer of immunoglobulin G in Majorera goat kids [J].

Castro, N ;

Capote, J ;

Alvarez, S ;

Argüello, A .

JOURNAL OF DAIRY SCIENCE, 2005, 88 (10) :3650-3654

[5] Cell proliferation, apoptosis, and B- and T-lymphocytes in Peyer's patches of the ileum, in thymus and in lymph nodes of preterm calves, and in full-term calves at birth and on day 5 of life [J].

David, CW ;

Norrman, J ;

Hammon, HM ;

Davis, WC ;

Blum, JW .

JOURNAL OF DAIRY SCIENCE, 2003, 86 (10) :3321-3329

[6] AN IMMUNOELECTRON MICROSCOPIC INVESTIGATION OF COLOSTRAL IGG ABSORPTION ACROSS THE INTESTINE OF NEWBORN CALVES [J].

JOCHIMS, K ;

KAUP, FJ ;

DROMMER, W ;

PICKEL, M .

RESEARCH IN VETERINARY SCIENCE, 1994, 57 (01) :75-80

[7] Redistribution of the sheep neonatal Fc receptor in the mammary gland around the time of parturition in ewes and its localization in the small intestine of neonatal lambs [J].

Mayer, B ;

Zolnai, A ;

Frenyó, LV ;

Jancsik, V ;

Szentirmay, Z ;

Hammarström, L ;

Kacskovics, I .

IMMUNOLOGY, 2002, 107 (03) :288-296

[8] Enterocyte proliferation and apoptosis in the caudal small intestine is influenced by the composition of colonizing commensal bacteria in the neonatal gnotobiotic pig [J].

Willing, B. P. ;

Van Kessel, A. G. .

JOURNAL OF ANIMAL SCIENCE, 2007, 85 (12) :3256-3266

← 1 →