Mild cognitive impairment and dementia

被引：39
作者：
Albert, Marilyn S. [1 ]
Blacker, Deborah [2 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21212 USA
[2] Harvard Univ, Sch Med, Dept Psychiat, Massachusetts Gen Hosp, Boston, MA 02114 USA
来源：
ANNUAL REVIEW OF CLINICAL PSYCHOLOGY | 2006年 / 2卷
关键词：
Alzheimer's disease; MCI; biomarkers; APOE; clinical trials;
D O I：
10.1146/annurev.clinpsy.1.102803.144039
中图分类号：
B849 [应用心理学];
学科分类号：
040203 ;
摘要：
Mild cognitive impairment (MCI) is a clinical syndrome thought to represent the transition between normal function and dementia. This review describes data that support the existence of such a transitional phase, outlines the heterogeneity of MCI and how that has influenced the evolving concept of MCI, and discusses the impact of heterogeneity on recent MCI clinical trials.
引用
收藏
页码：379 / 388
页数：10
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