A phytochemical study of the quinolizidine alkaloids from Genista tenera by gas chromatography-mass spectrometry

被引:22
作者
Martins, A
Wink, M
Tei, A
Brum-Bousquet, M
Tillequin, F
Rauter, AP
机构
[1] Univ Lisbon, Fac Ciencias, Dept Quim & Bioquim, P-1749016 Lisbon, Portugal
[2] Univ Heidelberg, Inst Pharm & Mol Biotechnol, D-69120 Heidelberg, Germany
[3] Univ Paris 05, Fac Pharm, CNRS,UMR 8638, Lab Pharmacognosie, F-75006 Paris, France
关键词
GC-MS; quinolizidine alkaloids; Genista tenera; Fabaceae;
D O I
10.1002/pca.832
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Gas chromatography coupled with mass spectrometry has been used to analyse the alkaloids present in the aerial parts of Genista tenera. Anagyrine, cytisine, N-formylcytisine, N-methylcytisine and lupanine were the major compounds, the last two alkaloids being known for their hypoglycaemic activity. Dehydrocytisine, 5,6-dehydrolupanine, rhombifoline, aphylline and thermopsine were the minor alkaloids. The characterisation of the constituents was based on comparison of their Kovats retention indexes and electron impact-mass spectrometric data recorded on-line with those of reference compounds and literature data. Copyright (C) 2005 John Wiley & Sons, Ltd.
引用
收藏
页码:264 / 266
页数:3
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