Roles of the hypocretin/orexins in the regulation of sleep and wakefulness

被引：0
作者：
Terao, Akira [1 ]
Haruyama, Takashi [1 ]
Kimura, Kazuhiro [1 ]
机构：
[1] Hokkaido Univ, Grad Sch Vet Med, Dept Biomed Sci, Biochem Lab, Sapporo, Hokkaido 0600818, Japan
来源：
JAPANESE JOURNAL OF VETERINARY RESEARCH | 2008年 / 55卷 / 2-3期
关键词：
hypocretin; orexin; narcolepsy; sleep; wakefulness;
D O I：
暂无
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Hypocretin/orexin is produced exclusively in the dorsal and lateral hypothalamus but its projection is widespread within the brain and plays important roles. In this paper, we review the independent discoveries of the hypocretin/orexin peptides, the neuroanatomy of this system, and the link to the sleep disorder narcolepsy that has led to the idea that this system plays a crucial role in the regulation of sleep and wakefulness.
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页码：75 / 83
页数：9
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