SYNTHESIS AND ANALGESIC ACTIVITY OF N′,N′-DIALKYLHYDRADIZES OF ALIPHATIC CARBOXYLIC ACIDS

被引：0

作者：

Batueva, T. D. ^{[1
]}

Anikina, L. V. ^{[1
]}

Gusev, V. Yu. ^{[1
]}

Maiorova, O. A. ^{[1
]}

Radushev, A. V. ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Tech Chem, Ural Branch, Perm, Russia

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2010年 / 44卷 / 04期

关键词：

N; N '-dialkylhydrazides of aliphatic carboxylic acids; synthesis; analgesic activity;

D O I：

10.1007/s11094-010-0429-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of new N',N'-dialkylhydrazides of aliphatic carboxylic acids have been obtained. It is shown that some of these compounds possess central analgesic activity and exhibit low toxicity. N',N'-dialkylhydrazides of octanoic acid are of interest for further investigation in the search for new neurotropic agents.

引用

页码：192 / 194

页数：3