Three new taxoids from the leaves of the Japanese yew, Taxus cuspidata

被引：8

作者：

Shi, QW

Oritani, T

Kiyota, H

Murakami, R

机构：

[1] Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Lab Appl Bioorgan Chem,Aoba Ku, Sendai, Miyagi 9818555, Japan

[2] Univ Tokyo, Inst Mol & Cellular Biosci, Tokyo, Japan

来源：

NATURAL PRODUCT LETTERS | 2001年 / 15卷 / 01期

关键词：

Taxus cuspidata; Taxaceae; taxoids; leaves;

D O I：

10.1080/10575630108041258

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three new taxane diterpenoids were isolated from the leaves of the Japanese yew, Taxus cuspidta. Their structures were established as 5 alpha ,13 alpha -diacetoxy-taxa-4(20),11-diene-9 alpha ,10 beta -diol (1), 7 beta ,13 alpha -diacetoxy-5 alpha -cinnamyloxy-2(3-->20)-abeo-taxa-4(20), 11-diene-2 alpha ,10 beta -diol (2), and 2 alpha ,10 beta ,13 alpha -triacetoxy-taxa-4(20),11-diene-5 alpha ,7 beta ,9 alpha -triol (3)respectively on the basis of 1D and 2D NMR data.

引用

页码：55 / 62

页数：8

共 9 条

[1]

APPENDINO G, 1995, PHARM LIBR, V22, P55

[2] The taxane diterpenoids [J].