Briarane-type diterpenoids from the Vietnamese gorgonian Junceella fragilis

被引：9

作者：

Ngoc Ninh Thi ^{[1
]}

Hanh Tran Thi Hong ^{[1
]}

Thanh Nguyen Van ^{[1
]}

Cuong Nguyen Xuan ^{[1
]}

Nam Nguyen Hoai ^{[1
]}

Thung Do Cong ^{[2
]}

Kiem Phan Van ^{[1
]}

Minh Chau Van ^{[1
]}

机构：

[1] Vietnam Acad Sci & Technol, Inst Marine Biochem, Hanoi, Vietnam

[2] VAST, Inst Marine Environm & Resources, Haiphong, Vietnam

来源：

NATURAL PRODUCT RESEARCH | 2020年 / 34卷 / 03期

关键词：

Junceella fragilis; gorgonian; briarane; cytotoxic activity; NATURAL-PRODUCT CHEMISTRY; CORALS;

D O I：

10.1080/14786419.2018.1534850

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Ten briarane-type diterpenoids (1-10), including one new stereoisomer 17-epi-junceellolide B (1), were isolated from the MeOH extract of the Vietnamese gorgonian Junceella fragilis. Their structures were elucidated by spectroscopic experiments including 1D and 2D NMR, and HR-QTOF-MS. In addition, the in vitro cytotoxic activity against eight human cancer cell lines (LNCaP, HepG2, KB, MCF-7, SK-Mel2, HL-60, LU-1 and SW480) of all isolated compounds was evaluated by SRB assays.

引用

页码：385 / 389

页数：5

共 15 条

[1] Structures and absolute stereochemistry of guaiane sesquiterpenoids from the gorgonian Menella woodin [J].

Chau Ngoc Diep ;

Lyakhova, Ekaterina G. ;

Berdyshev, Dmitrii V. ;

Kalinovsky, Anatoly I. ;

Vu Anh Tu ;

Nguyen Xuan Cuong ;

Nguyen Hoai Nam ;

Chau Van Minh ;

Stonik, Valentin A. .

TETRAHEDRON LETTERS, 2015, 56 (50) :7001-7004

[2] Halogenated Briarane Diterpenes with Acetyl Migration from the Gorgonian Coral Junceella fragilis [J].

Cheng, Wei ;

Li, Xiaodan ;

Yin, Fuling ;

van Ofwegen, Leen ;

Lin, Wenhan .

CHEMISTRY & BIODIVERSITY, 2017, 14 (05)

[3] Absolute structures of new briarane diterpenoids from Junceella fragilis [J].

García, M ;

Rodríguez, J ;

Jiménez, C .

JOURNAL OF NATURAL PRODUCTS, 1999, 62 (02) :257-260

[4] FEASIBILITY OF A HIGH-FLUX ANTICANCER DRUG SCREEN USING A DIVERSE PANEL OF CULTURED HUMAN TUMOR-CELL LINES [J].

MONKS, A ;

SCUDIERO, D ;

SKEHAN, P ;

SHOEMAKER, R ;

PAULL, K ;

VISTICA, D ;

HOSE, C ;

LANGLEY, J ;

CRONISE, P ;

VAIGROWOLFF, A ;

GRAYGOODRICH, M ;

CAMPBELL, H ;

MAYO, J ;

BOYD, M .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1991, 83 (11) :757-766

[5] Pregnane steroids from the Vietnamese octocoral Carijoa riisei [J].

Nam Nguyen Hoai ;

Huong Nguyen Thi ;

Hanh Tran Thi Hong ;

Thanh Nguyen Van ;

Cuong Nguyen Xuan ;

Thung Do Cong ;

Kiem Phan Van ;

Minh Chau Van .

NATURAL PRODUCT RESEARCH, 2017, 31 (20) :2435-2440

[6] Cytotoxic steroids from the Vietnamese gorgonian Verrucella corona [J].

Nguyen Hoai Nam ;

Ninh Thi Ngoc ;

Tran Thi Hong Hanh ;

Nguyen Xuan Cuong ;

Nguyen Van Thanh ;

Do Thi Thao ;

Do Cong Thung ;

Phan Van Kiem ;

Chau Van Minh .

STEROIDS, 2018, 138 :57-63

[7] New briaranes from the South China Sea gorgonian Junceella fragilis [J].

Qi, SH ;

Zhang, S ;

Wen, YM ;

Xiao, ZH ;

Li, QX .

HELVETICA CHIMICA ACTA, 2005, 88 (08) :2349-2354

[8] THE JUNCEELLOLIDES, NEW ANTI-INFLAMMATORY DITERPENOIDS OF THE BRIARANE CLASS FROM THE CHINESE GORGONIAN JUNCEELLA-FRAGILIS [J].

SHIN, J ;

PARK, M ;

FENICAL, W .

TETRAHEDRON, 1989, 45 (06) :1633-1638

[9] Briarane Diterpenoids Isolated from Octocorals between 2014 and 2016 [J].

Su, Yin-Di ;

Su, Jui-Hsin ;

Hwang, Tsong-Long ;

Wen, Zhi-Hong ;

Sheu, Jyh-Horng ;

Wu, Yang-Chang ;

Sung, Ping-Jyun .

MARINE DRUGS, 2017, 15 (02)

[10] Natural product chemistry of gorgonian corals of the genus Junceella [J].

Sung, PJ ;

Gwo, HH ;

Fan, TY ;

Li, JJ ;

Dong, J ;

Han, CC ;

Wu, SL ;

Fang, LS .

BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2004, 32 (02) :185-196

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