Urtica dioica-Derived Phytochemicals for Pharmacological and Therapeutic Applications

被引：66

作者：

Taheri, Yasaman ^{[1
]}

Quispe, Cristina ^{[2
]}

Herrera-Bravo, Jesus ^{[3
,4
]}

Sharifi-Rad, Javad ^{[1
,5
]}

Ezzat, Shahira M. ^{[6
,7
]}

Merghany, Rana M. ^{[8
]}

Shaheen, Shabnum ^{[9
]}

Azmi, Lubna ^{[10
]}

Mishra, Abhay Prakash ^{[11
]}

Sener, Bilge ^{[12
]}

Kilic, Mehtap ^{[13
]}

Sen, Surjit ^{[14
,15
]}

Acharya, Krishnendu ^{[14
]}

Nasiri, Azadeh ^{[16
]}

Cruz-Martins, Natalia ^{[17
,18
,19
,20
]}

Fokou, Patrick Valere Tsouh ^{[21
]}

Ydyrys, Alibek ^{[22
]}

Bassygarayev, Zhandos ^{[23
]}

Dastan, Sevgi Durna ^{[24
,25
]}

Alshehri, Mohammed M. ^{[26
]}

Calina, Daniela ^{[27
]}

Cho, William C. ^{[28
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Phytochem Res Ctr, Tehran, Iran

[2] Univ Arturo Prat, Fac Ciencias Salud, Avda Arturo Prat 2120, Iquique 1110939, Chile

[3] Univ Santo Tomas, Fac Ciencias, Dept Ciencias Basicas, Santiago, Chile

[4] Univ La Frontera, Ctr Mol Biol & Pharmacogenet, Sci & Technol Bioresource Nucleus, Temuco 4811230, Chile

[5] Univ Azuay, Fac Med, Cuenca, Ecuador

[6] Cairo Univ, Fac Pharm, Dept Pharmacognosy, Kasr El Ainy St, Cairo 11562, Egypt

[7] October Univ Modern Sci & Arts MSA, Fac Pharm, Dept Pharmacognosy, 6th Of October 12451, Egypt

[8] Natl Res Ctr, Dept Pharmacognosy, Giza, Egypt

[9] LCWU, Dept Plant Sci, Lahore 54000, Pakistan

[10] Hygia Inst Pharmaceut Educ & Res, Lucknow 226001, Uttar Pradesh, India

[11] Univ Free State, Dept Pharmacol, ZA-9300 Bloemfontein, Free State, South Africa

[12] Gazi Univ, Fac Pharm, Dept Pharmacognosy, TR-06330 Ankara, Turkey

[13] Lokman Hekim Univ, Dept Pharmacognosy, Fac Pharm, TR-06510 Ankara, Turkey

[14] Univ Calcutta, Dept Bot, Mol & Appl Mycol & Plant Pathol Lab, Kolkata 700019, India

[15] Fakir Chand Coll, Dept Bot, Diamond Harbour 743331, W Bengal, India

[16] Shahid Beheshti Univ Med Sci, Sch Pharm, Dept Pharmacol & Toxicol, Tehran, Iran

[17] Univ Porto, Fac Med, Porto, Portugal

[18] Univ Porto, Inst Res & Innovat Hlth I3S, Porto, Portugal

[19] Inst Res & Adv Training Hlth Sci & Technol CESPU, Rua Cent Gandra 1317, P-4585116 Gandra, Prd, Portugal

[20] Univ Inst Hlth Sci, TOXRUN Oxicol Res Unit, CRL, CESPU, P-4585116 Gandra, Portugal

[21] Univ Bamenda, Fac Sci, Dept Biochem, POB 39, Bambili, Cameroon

[22] Al Farabi Kazakh Natl Univ, Biomed Res Ctr, Al Farabi Av 71, Alma Ata 050040, Kazakhstan

[23] Al Farabi Kazakh Natl Univ, Dept Biophys Biomed & Neurosci, Al Farabi Av 71, Alma Ata 050040, Kazakhstan

[24] Sivas Cumhuriyet Univ, Fac Sci, Dept Biol, TR-58140 Sivas, Turkey

[25] Sivas Cumhuriyet Univ, Beekeeping Dev Applicat & Res Ctr, TR-58140 Sivas, Turkey

[26] Minist Natl Guard Hlth Affairs, Pharmaceut Care Dept, Riyadh, Saudi Arabia

[27] Univ Med & Pharm Craiova, Dept Clin Pharm, Craiova 200349, Romania

[28] Queen Elizabeth Hosp, Dept Clin Oncol, Kowloon, Hong Kong, Peoples R China

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2022年 / 2022卷

关键词：

EXTRACT INHIBITS PROLIFERATION; IN-VITRO; AQUEOUS EXTRACT; ANTIINFLAMMATORY ACTIVITIES; CHEMICAL-COMPOSITION; DENTATA HAND; LEAF EXTRACT; DOUBLE-BLIND; ANTIOXIDANT; L;

D O I：

10.1155/2022/4024331

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Urtica dioica belongs to the Urticaceae family and is found in many countries around the world. This plant contains a broad range of phytochemicals, such as phenolic compounds, sterols, fatty acids, alkaloids, terpenoids, flavonoids, and lignans, that have been widely reported for their excellent pharmacological activities, including antiviral, antimicrobial, antihelmintic, anticancer, nephroprotective, hepatoprotective, cardioprotective, antiarthritis, antidiabetic, antiendometriosis, antioxidant, anti-inflammatory, and antiaging effects. In this regard, this review highlights fresh insight into the medicinal use, chemical composition, pharmacological properties, and safety profile of U. dioica to guide future works to thoroughly estimate their clinical value.

引用

页数：30

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