Enantioselective Synthesis of Indole Alkaloids from Chiral Lactams

被引：53
作者：
Amat, Mercedes [1 ]
Perez, Maria
Bosch, Joan
机构：
[1] Univ Barcelona, Fac Pharm, Organ Chem Lab, E-08028 Barcelona, Spain
来源：
SYNLETT | 2011年 / 02期
关键词：
alkaloids; lactams; indoles; stereoselective synthesis; total synthesis; DYNAMIC KINETIC RESOLUTION; STEREOSELECTIVE ALPHA-AMIDOALKYLATION; RACEMIC BICYCLIC LACTAMS; ASYMMETRIC-SYNTHESIS; FORMAL SYNTHESIS; RECENT PROGRESS; STRAIGHTFORWARD METHODOLOGY; DESYMMETRIZATION PROCESSES; ENANTIODIVERGENT SYNTHESIS; QUINOLIZIDINE ALKALOIDS;
D O I：
10.1055/s-0030-1259297
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
This account reports on the use of (R)- or (S)-phenylglycinol- and (S)-tryptophanol-derived oxazolopiperidone lactams as building blocks for the enantioselective synthesis of structurally diverse indole alkaloids.
引用
收藏
页码：143 / 160
页数：18
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