Enantioselective Synthesis of Indole Alkaloids from Chiral Lactams

被引：53

作者：

Amat, Mercedes ^{[1
]}

Perez, Maria

Bosch, Joan

机构：

[1] Univ Barcelona, Fac Pharm, Organ Chem Lab, E-08028 Barcelona, Spain

来源：

SYNLETT | 2011年 / 02期

关键词：

alkaloids; lactams; indoles; stereoselective synthesis; total synthesis; DYNAMIC KINETIC RESOLUTION; STEREOSELECTIVE ALPHA-AMIDOALKYLATION; RACEMIC BICYCLIC LACTAMS; ASYMMETRIC-SYNTHESIS; FORMAL SYNTHESIS; RECENT PROGRESS; STRAIGHTFORWARD METHODOLOGY; DESYMMETRIZATION PROCESSES; ENANTIODIVERGENT SYNTHESIS; QUINOLIZIDINE ALKALOIDS;

D O I：

10.1055/s-0030-1259297

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This account reports on the use of (R)- or (S)-phenylglycinol- and (S)-tryptophanol-derived oxazolopiperidone lactams as building blocks for the enantioselective synthesis of structurally diverse indole alkaloids.

引用

页码：143 / 160

页数：18

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