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Unexpected synthesis of aziridines under Cu(I) catalyzed Kinugasa conditions assisted by microwave irradiation
被引:5
|作者:
Abda, Heithem
[1
]
Aouadi, Kaiss
[1
]
Brahmi, Jihed
[1
]
Msaddek, Moncef
[1
]
Vidal, Sebastien
[2
]
机构:
[1] Univ Monastir, Fac Sci Monastir, Lab Synth Heterocycl Prod Nat & React, Ave Environm, Monastir 5000, Tunisia
[2] Univ Lyon, Inst Chim & Biochim Mol & Supramol, UMR CNRS 5246, Lab Chim Organ Glycochim 2, Batiment Curien,43 Blvd 11 Novembre 1918, F-69622 Villeurbanne, France
关键词:
Nitrone;
Alkynes;
1,3-Dipolar cycloaddition;
Aziridines;
Microwaves;
1,3-DIPOLAR CYCLOADDITION;
CHIRAL NITRONES;
4-ISOXAZOLINES;
REARRANGEMENT;
ALKYNES;
ACYLAZIRIDINES;
DERIVATIVES;
ALKENES;
D O I:
10.1016/j.crci.2015.09.009
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
Cu(I)-catalyzed 1,3-dipolar cycloaddition between chiral nitrone and terminal alkynes under microwave irradiation afforded a series of enantiopure aziridines with the creation of two contiguous stereogenic centers. (C) 2015 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.
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页码:275 / 278
页数:4
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