A new reactivity pattern for vinyl bromides:: cine-substitution via palladium catalysed C-N coupling/Michael addition reactions

被引：30
作者：
Willis, MC [1 ]
Chauhan, J
Whittingham, WG
机构：
[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England
[2] Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2005年 / 3卷 / 17期
关键词：
D O I：
10.1039/b508464d
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium catalysed C-N bond formation can be used to convert vinyl bromides to the corresponding enamines, which are reacted in situ with alkylidene malonates to provide Michael adducts. The overall transformation results in cine-substitution of the starting vinyl bromide.
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收藏
页码：3094 / 3095
页数：2
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