Synthesis, crystal structure and spectroscopic characterizations of porphyrin-based Mg(II) complexes - Potential application as antibacterial agent

We reported the synthesis, spectral and photophysical studies of H2TBrPP (5,10,15,20-tetrakis(4-bromophenyl)porphyrin), Mg(TBrPP), and the complex [Mg(TBrPP)(HIm)] (I) (Him = Imidazole). A detailed analysis of infrared, and proton nuclear magnetic resonance spectroscopies, mass spectrometry, and elemental analysis are in good agreement with the transformation of the free base porphyrin H2TBrPP to the porphyrinic Mg(II) complex and to the one involving a bonded imidazole ligand. The photophysical properties were investigated by UV-visible absorption, and emission spectroscopies. New complex 1 was also characterized by single crystal X-ray diffraction confirming the pentacoordination of the Mg(II) ion within a new meso-porphyrin complex, an imidazole molecule in an axial position completing the ligand sphere. Potential use of this complex as a novel antibacterial agent was also investigated. (C) 2017 Elsevier Ltd. All rights reserved.