Matched-pair analysis of survival in the patients with T3 laryngeal squamous cell carcinoma treated with supracricoid partial laryngectomy or total laryngectomy

被引：10
作者：
Xial, Xin [1 ,2 ]
Zhu, Ying-Ying [1 ,2 ]
Diao, Wen-Wen [1 ,2 ]
Zhu, Xiao-Li [1 ,2 ]
Shi, Xiao-Hua [2 ,3 ]
Li, Wu-Yi [1 ,2 ]
Gao, Zhi-Qiang [1 ,2 ]
Li, Guo-Jun [1 ,2 ]
Chen, Xing-Ming [1 ,2 ]
机构：
[1] Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Otolaryngol Head & Neck Surg, 1 Shuaifuyuan, Beijing 100730, Peoples R China
[2] Chinese Acad Med Sci, 1 Shuaifuyuan, Beijing 100730, Peoples R China
[3] Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Pathol, Beijing, Peoples R China
来源：
ONCOTARGETS AND THERAPY | 2018年 / 11卷
关键词：
survival analysis; matched-pair analysis; laryngeal neoplasms; laryngectomy; squamous cell carcinoma; CRICOHYOIDOPEXY; CANCER; CRICOHYOIDOEPIGLOTTOPEXY; PRESERVATION; OUTCOMES; T3-T4;
D O I：
10.2147/OTT.S175358
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Background: The survival outcomes between supracricoid partial laryngectomy (SCPL) and total laryngectomy (TL) were compared in the groups of matched-pair patients with T3 laryngeal squamous cell carcinoma (LSCC). Methods: Patients with T3 LSCC were matched based on prognostic factors. The Kaplan-Meier curve and the Cox proportional hazards model were used for analysis on survival. Results: A total of 212 patients with T3 LSCC were included after matching (106 underwent SCPL and 106 underwent TL). Multivariable analysis showed no differences in overall survival (hazard risk [HR]=1.15; 95% CI: 0.79-1.67; P=0.47), disease-specific survival (HR=1.11; 95% CI: 0.69-1.80; P=0.66), and recurrence-free survival (HR=1.07; 95% CI: 0.68-1.68; P=0.77) between the SCPL group and TL group. Conclusion: SCPL provides reliable therapeutic outcomes and can be used to avoid a TL surgery in sonic patients with advanced primary laryngeal cancer.
引用
收藏
页码：7947 / 7953
页数：7
相关论文
共 30 条
[21]   Clinical nodal stage is an independently significant predictor of distant failure in patients with squamous cell carcinoma of the larynx [J].
Matsuo, JMS ;
Patel, SG ;
Singh, B ;
Wong, RJ ;
Boyle, JO ;
Kraus, DH ;
Shaha, AR ;
Zelefsky, MJ ;
Pfister, DG ;
Shah, JP .
ANNALS OF SURGERY, 2003, 238 (03) :412-421
[22]  
Mercante G, 2013, OTOLARYNG HEAD NECK, V149, P714, DOI 10.1177/0194599813500018
[23]   Post-Surgical and Oncologic Outcomes of Supracricoid Partial Laryngectomy: A Single-Institution Report of Ninety Cases [J].
Ozturk, Kerem ;
Akyildiz, Serdar ;
Gode, Sercan ;
Turhal, Goksel ;
Kirazli, Tayfun ;
Aysel, Abdulhalim ;
Uluoz, Umit .
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY HEAD AND NECK SURGERY, 2016, 78 (02) :86-93
[24]  
Piquet J J, 1974, Ann Otolaryngol Chir Cervicofac, V91, P681
[25]   Matched-pair analysis of survival of never smokers and ever smokers with squamous cell carcinoma of the head and neck [J].
Pytynia, KB ;
Grant, JR ;
Etzel, CJ ;
Roberts, DB ;
Wei, QY ;
Sturgis, EM .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (19) :3981-3988
[26]   Subtotal laryngectomy: outcomes of 469 patients and proposal of a comprehensive and simplified classification of surgical procedures [J].
Rizzotto, G. ;
Crosetti, E. ;
Lucioni, M. ;
Succo, G. .
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2012, 269 (06) :1635-1646
[27]   Results of total laryngectomy as treatment for locally advanced laryngeal cancer in the organ-preservation era [J].
Rodrigo, Juan P. ;
Lopez, Fernando ;
Llorente, Jose L. ;
Alvarez-Marcos, Cesar ;
Suarez, Carlos .
ACTA OTORRINOLARINGOLOGICA ESPANOLA, 2015, 66 (03) :132-138
[28]   Supracricoid partial laryngectomy: an alternative to total laryngectomy for locally advanced laryngeal cancers [J].
Soudry, E. ;
Marmor, Y. ;
Hazan, A. ;
Marx, S. ;
Sadov, R. ;
Feinmesser, R. .
JOURNAL OF LARYNGOLOGY AND OTOLOGY, 2008, 122 (11) :1219-1223
[29]   Laryngeal preservation with supracricoid partial laryngectomy results in improved quality of life when compared with total laryngectomy [J].
Weinstein, GS ;
El-Sawy, MM ;
Ruiz, C ;
Dooley, P ;
Chalian, A ;
El-Sayed, MM ;
Goldberg, A .
LARYNGOSCOPE, 2001, 111 (02) :191-199
[30]   Supracricoid partial laryngectomy cricohyoidoepiglottopexy (SCPL-CHEP) versus vertical partial laryngectomy for the treatment of glottic carcinoma [J].
Zhang, Si-Yi ;
Lu, Zhong-Ming ;
Chen, Liang-Si ;
Luo, Xiao-Ning ;
Ge, Ping-Jiang ;
Song, Xin-Han ;
Chen, Shao-Hua ;
Wu, Yi-Long .
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2013, 270 (03) :1027-1034
123