Combinational therapy by targeting LSD1 and BRD4 in prostate cancer

被引:0
|
作者
Li, Muqing [1 ]
Han, Dong [1 ]
Wang, Zifeng [1 ]
Gao, Shuai [1 ]
Cai, Changmeng [1 ]
机构
[1] UMass Boston, Boston, MA USA
关键词
D O I
10.1158/1535-7163.TARG-19-LB-A14
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
LB-A14
引用
收藏
页数:2
相关论文
共 50 条
  • [1] The combined effect of epigenetic inhibitors for LSD1 and BRD4 alters prostate cancer growth and invasion
    Wang, Jianlin
    Yu, Qian
    Qiu, Zhaoping
    Dai, Tao
    Wang, Shuxia
    Yang, Xiuwei
    Evers, B. Mark
    Wu, Yadi
    AGING-US, 2020, 12 (01): : 397 - 415
  • [2] Targeting prostate cancer super enhancers by co-inhibiting LSD1 and BRD4.
    Gao, Shuai
    Li, Muqing
    Liu, Mingyu
    Han, Dong
    Wang, Zifeng
    Han, Wanting
    Cai, Changmeng
    CANCER RESEARCH, 2021, 81 (13)
  • [3] Targeting Brd4 for cancer therapy: inhibitors and degraders
    Duan, Yingchao
    Guan, Yuanyuan
    Qin, Wenping
    Zhai, Xiaoyu
    Yu, Bin
    Liu, Hongmin
    MEDCHEMCOMM, 2018, 9 (11) : 1779 - 1802
  • [4] LSD1 activates oncogenic super-enhancers in castration-resistant prostate cancer by forming nuclear condensates with BRD4
    Liu, Mingyu
    Li, Muqing
    Han, Dong
    Wang, Zifeng
    Han, Wanting
    He, Housheng Hansen
    Gao, Shuai
    Cai, Changmeng
    CANCER RESEARCH, 2023, 83 (07)
  • [5] Targeting LSD1 and FOXA1 in prostate cancer
    Omarjee, Soleilmane
    Carroll, Jason S.
    NATURE GENETICS, 2020, 52 (10) : 1002 - 1003
  • [6] Targeting LSD1 and FOXA1 in prostate cancer
    Soleilmane Omarjee
    Jason S. Carroll
    Nature Genetics, 2020, 52 : 1002 - 1003
  • [7] Rational combinational therapy with PARP and BRD4 inhibitor in ovarian cancer.
    Sun, Chaoyang
    Yin, Jun
    Fang, Yong
    Mills, Gordon B.
    CLINICAL CANCER RESEARCH, 2018, 24 (15) : 42 - 42
  • [8] C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4
    Bruno Di Stefano
    Samuel Collombet
    Janus Schou Jakobsen
    Michael Wierer
    Jose Luis Sardina
    Andreas Lackner
    Ralph Stadhouders
    Carolina Segura-Morales
    Mirko Francesconi
    Francesco Limone
    Matthias Mann
    Bo Porse
    Denis Thieffry
    Thomas Graf
    Nature Cell Biology, 2016, 18 : 371 - 381
  • [9] C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4
    Di Stefano, Bruno
    Collombet, Samuel
    Jakobsen, Janus Schou
    Wierer, Michael
    Luis Sardina, Jose
    Lackner, Andreas
    Stadhouders, Ralph
    Segura-Morales, Carolina
    Francesconi, Mirko
    Limone, Francesco
    Mann, Matthias
    Porse, Bo
    Thieffry, Denis
    Graf, Thomas
    NATURE CELL BIOLOGY, 2016, 18 (04) : 371 - +
  • [10] Targeting oral cancer epigenome via LSD1
    Bais, Manish V.
    AGING-US, 2017, 9 (12): : 2455 - 2456