MicroRNA functions

被引：2473

作者：

Bushati, Natascha ^{[1
]}

Cohen, Stephen M. ^{[1
]}

机构：

[1] European Mol Biol Lab, Dev Biol Unit, D-69117 Heidelberg, Germany

来源：

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY | 2007年 / 23卷

关键词：

posttranscriptional gene regulation; development; disease; genetics;

D O I：

10.1146/annurev.cellbio.23.090506.123406

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

microRNAs (miRNAs) are small noncoding RNAs that play important roles in posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by translational inhibition and mRNA destabilization. Here, we review recent work in animal models that provide insight into the diverse roles of miRNAs in vivo.

引用

页码：175 / 205

页数：31

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