Eudesmane-type sesquiterpenes from the liverwort Apomarsupella revolute

被引：7

作者：

Liu, Na ^{[1
]}

Zhang, Li ^{[1
]}

Wang, Song ^{[1
]}

Wang, Xiao-Ning ^{[1
]}

Wang, Shu-Qi ^{[1
]}

Lou, Hong-Xiang ^{[1
]}

机构：

[1] Shandong Univ, Sch Pharmaceut Sci, Dept Nat Prod Chem, Jinan 250012, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2012年 / 5卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Liverwort; Apomarsupella revolute; Eudesmane; Cytotoxicity; Antifungal activity; MARSUPELLA-EMARGINATA; CHEMICAL-CONSTITUENTS; CIRCULAR-DICHROISM; DITERPENOIDS; DERIVATIVES;

D O I：

10.1016/j.phytol.2012.02.016

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical investigation of the Et2O extract of liverwort Apomarsupella revolute led to isolation and identification of five new eudesmane-type sesquiterpenoids, 6 beta-hydroxy-9 beta-acetoxy-eudesma-4,11-dien (1), 6 beta-hydroxy-9 beta-acetoxy-eudesma-4,11-dien-3-one (2), 5 alpha, 6 beta-dihydroxy-9 beta-acetoxyeudesma-4(15), 11-dien (3) 4 beta-hydroxy-9 beta-acetoxy-11,12,13-trinor-5-eudesmen-7-one (4) and 4 beta-methox-9 beta-acetoxy-11,12,13-trinor-5-eudesmen-7-one (5), two of which were trinorsesquiterpenoids. Their structures were established unequivocally on the basis of spectroscopic data analysis. All compounds were preliminary bioscreened for their cytotoxicities and antifungal activities. (C) 2012 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.

引用

页码：346 / 350

页数：5

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