Comparison of the clinical characteristics and outcomes of Klebsiella pneumoniae and Streptococcus pneumoniae meningitis

被引:15
作者
Jung, Jiwon [1 ]
Park, Ki-Ho [2 ]
Park, Seong Yeon [3 ]
Song, Eun Hee [4 ]
Lee, Eun Jung [5 ]
Choi, Seong-Ho [6 ]
Choo, Eun Ju [7 ]
Kwak, Yee Gyung [8 ]
Sung, Heungsup [9 ]
Kim, Sung-Han [1 ]
Lee, Sang-Oh [1 ]
Kim, Mi-Na [9 ]
Kim, Yang Soo [1 ]
Woo, Jun Hee [1 ]
Choi, Sang-Ho [1 ]
机构
[1] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Infect Dis, Seoul, South Korea
[2] Kyung Hee Univ, Kyung Hee Univ Hospital, Sch Med, Dept Internal Med,Div Infect Dis, Seoul, South Korea
[3] Dongguk Univ, Ilsan Hosp, Dept Internal Med, Div Infect Dis, Goyang, South Korea
[4] Univ Ulsan, Gangneung Asan Hosp, Coll Med, Dept Infect Dis, Kangnung, South Korea
[5] Soonchunhyang Univ Hosp, Dept Internal Med, Div Infect Dis, Seoul, South Korea
[6] Chung Ang Univ Hosp, Dept Internal Med, Div Infect Dis, Seoul, South Korea
[7] Soonchunhyang Univ, Bucheon Hosp, Dept Internal Med, Div Infect Dis, Bucheon, South Korea
[8] Inje Univ, Ilsan Paik Hosp, Dept Internal Med, Div Infect Dis, Goyarig, South Korea
[9] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Lab Med, Seoul, South Korea
关键词
Klebsiella pneumoniae; Streptococcus pneumoniae; Meningitis; PYOGENIC LIVER-ABSCESS; ACUTE BACTERIAL-MENINGITIS; SOUTHERN TAIWAN; PROGNOSTIC FACTORS; RISK-FACTORS; SEROTYPE K1; HONG-KONG; ADULTS; KOREA; EXPERIENCE;
D O I
10.1016/j.diagmicrobio.2015.02.006
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
This multicenter, retrospective cohort study compared the clinical characteristics and outcomes of community-acquired Klebsiella pneumoniae meningitis (CA-KPM). with those of community-acquired Streptococcus pneumoniae meningitis (CA-SPM). Eighty-three adult patients, 27 with CA-KPM and 56 with CA-SPM, were included. Diabetes mellitus (48.1% versus 21.4%; P = 0.01) and liver cirrhosis (22.2% versus 5.4%; P = 0.05) were more commonly associated with CA-KPM. Comatose mental status (40.7% versus 12.5%; P = 0.01), septic shock (44.4% versus 8.9%; P < 0.001), and concomitant extrameningeal infections (40.7% versus 7.1%; P = 0.001) were also more common in the CA-KPM group. The 28-day mortality (44.4% versus 10.7%; P < 0.001) and inhospital mortality (51.9% versus 14.3%; P < 0.001) were higher in the CA-KPM group. In conclusion, diabetes mellitus and liver cirrhosis are more common in the CA-KPM patients who were also more likely to present with severe manifestations and poor outcomes. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:87 / 91
页数:5
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