Application of optical coherence tomography attenuation imaging for quantification of optical properties in medulloblastoma

被引：0

作者：

Vuong, Barry ^{[1
,2
]}

Skowron, Patryk ^{[1
,3
,4
]}

Kiehl, Tim-Rasmus ^{[5
,6
]}

Kyan, Matthew ^{[2
]}

Garzi, Livia ^{[6
,7
,8
]}

Genis, Helen ^{[1
]}

Sun, Cuiru ^{[1
]}

Taylor, Michael D. ^{[2
,7
,8
,9
]}

Yang, Victor X. D. ^{[1
,9
,10
,11
]}

机构：

[1] Ryerson Univ, Biophoton & Bioengn Lab, Toronto, ON, Canada

[2] Ryerson Univ, Dept Elect & Comp Engn, Toronto, ON, Canada

[3] Hosp Sick Children, Arthur & Sonia Labatt Brain Tumour Res Ctr, Toronto, ON, Canada

[4] Div Neurosurg, Toronto, ON, Canada

[5] Univ Hlth Network, Dept Pathol, Toronto, ON, Canada

[6] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada

[7] Hosp Sick Children, Program Dev & Stem Cell Biol, Toronto, ON M5G 1X8, Canada

[8] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada

[9] Univ Toronto, Fac Med, Div Neurosurg, Toronto, ON, Canada

[10] Sunnybrook Res Inst, Phys Sci Brain Sci Res Program, Toronto, ON, Canada

[11] Sunnybrook Hlth Sci Ctr, Div Neurosurg, Toronto, ON M4N 3M5, Canada

来源：

OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XIX | 2015年 / 9312卷

关键词：

Optical Coherence Tomography; Optical characteristics; Cancer; CHILDREN; SYSTEM; BRAIN;

D O I：

10.1117/12.2080642

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The hemodynamic environment is known to play a crucial role in the progression, rupture, and treatment of intracranial aneurysms. Currently there is difficulty assessing and measuring blood flow profiles in vivo. An emerging high resolution imaging modality known as split spectrum Doppler optical coherence tomography (ssDOCT) has demonstrated the capability to quantify hemodynamic patterns as well as arterial microstructural changes. In this study, we present a novel in vitro method to acquire precise blood flow patterns within a patientspecific aneurysm silicone flow models using ssDOCT imaging. Computational fluid dynamics (CFD) models were generated to verify ssDOCT results.

引用

页数：4

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