Chinese herbal medicine formula combined with calcium antagonist in the treatment of hypertension: a systematic review and meta-analysis

被引：0

作者：

Zhang, Qingyuan ^{[1
]}

Shao, Wenxiang ^{[1
]}

Xiao, Yonghuan ^{[2
]}

Wang, Yaling ^{[1
]}

Zhang, Jingwen ^{[1
]}

Ao, Meiying ^{[1
]}

机构：

[1] Jiangxi Univ Chinese Med, Evidence Based Med Res Ctr, Sch Tradit Chinese Med, Nanchang 330004, Jiangxi, Peoples R China

[2] Jiangxi Univ Chinese Med, Dept Pain Treatment, Affiliated Hosp, Nanchang, Jiangxi, Peoples R China

来源：

CLINICAL AND EXPERIMENTAL HYPERTENSION | 2022年 / 44卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Hypertension; traditional Chinese medicine; calcium antagonist; systematic evaluation; meta-analysis; UNITED-STATES; ALTERNATIVE MEDICINE; COMPLEMENTARY; MANAGEMENT; BURDEN; ADULTS; TRENDS;

D O I：

10.1080/10641963.2021.2013491

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Objective: Chinese herbal medicine formula and calcium antagonist are commonly used medicines for hypertension in China. This study aims to examine the efficacy and safety of for the treatment of Chinese herbal medicine formula combined calcium antagonist hypertension. Methods: PubMed, the Cochrane library, CNKI, VIP, Sinomed, and Wanfang Database were searched up to January 31, 2021. Data analysis was performed using the Recman 5.3. The source of clinical heterogeneity used stata16.0 for sensitivity analysis. Results: 17 RCTs and 1587 cases were finally included. The results shows that the traditional Chinese medicine decoction combined with calcium antagonists is better than calcium antagonists alone in the treatment of hypertension. In addition, it can effectively alleviate the adverse reactions caused by calcium antagonists. However, due to the low quality of methodology and the small-scale research, more high-quality clinical trials are still needed for verification.

引用

页码：181 / 190

页数：10

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