Impact of depression on HIV outcomes in the HAART era

被引：87

作者：

Hartzell, Joshua D. ^{[1
,2
]}

Janke, Igor E. ^{[3
]}

Weintrob, Amy C. ^{[1
,2
]}

机构：

[1] Walter Reed Army Med Ctr, Infect Dis Serv, Dept Med, Washington, DC 20307 USA

[2] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA

[3] Walter Reed Army Med Ctr, Dept Psychiat, Washington, DC 20307 USA

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2008年 / 62卷 / 02期

关键词：

AIDS; mental health; psychiatric;

D O I：

10.1093/jac/dkn193

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Highly active antiretroviral therapy (HAART) has significantly decreased the morbidity and mortality of persons infected with HIV. The extent of the benefits, however, is not uniform, and certain factors including ethnicity, gender, baseline HIV viral load and CD4+ T lymphocyte count, adherence and intravenous drug abuse are associated with different immunological, virological and clinical outcomes. Mental health illness (MHI) and specifically depression may be associated with worse outcomes, although studies exploring the impact of MHI on HIV outcomes in both the pre-HAART and post-HAART eras have shown mixed results. The objective of the current paper is to review the available literature on the impact of MHI on HIV outcomes in the HAART era.

引用

页码：246 / 255

页数：10

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