Mitochondrial translation, dynamics, and lysosomes combine to extend lifespan

被引：2

作者：

Ali, Levi ^{[1
]}

Haynes, Cole M. ^{[1
]}

机构：

[1] Univ Massachusetts, Med Sch, Dept Mol Cell & Canc Biol, Worcester, MA 01605 USA

来源：

JOURNAL OF CELL BIOLOGY | 2020年 / 219卷 / 06期

关键词：

D O I：

10.1083/jcb.202005084

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In this issue, Liu et al. (2019. J. Cell. Biol. https://doi.org/10.1083/jcb.201907067) find that the inhibition of mitochondrial ribosomes in combination with impaired mitochondrial fission or fusion increases C. elegans lifespan by activating the transcription factor HLH-30, which promotes lysosomal biogenesis.

引用

页数：2

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