Oxidative Stress and Nutraceuticals in the Modulation of the Immune Function: Current Knowledge in Animals of Veterinary Interest

被引:54
作者
Colitti, Monica [1 ]
Stefanon, Bruno [1 ]
Gabai, Gianfranco [2 ]
Gelain, Maria Elena [2 ]
Bonsembiante, Federico [2 ]
机构
[1] Univ Udine, Dept Agrifood Environm & Anim Sci, Via Sci 208, I-33100 Udine, Italy
[2] Univ Padua, Dept Comparat Biomed & Food Sci, Viale Univ 15, I-35020 Legnaro, PD, Italy
关键词
veterinary medicine; reactive oxygen species/reactive nitrogen species (ROS/RNS); immune system; regulation; nutraceutical; MESSENGER-RNA EXPRESSION; CENTRAL-NERVOUS-SYSTEM; BROWN ADIPOSE-TISSUE; PROTEIN PRODUCTS; SUPEROXIDE-DISMUTASE; CYTOKINE PRODUCTION; BOVINE NEUTROPHILS; GENE-EXPRESSION; PLANT-EXTRACTS; CANINE MODEL;
D O I
10.3390/antiox8010028
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In the veterinary sector, many papers deal with the relationships between inflammation and oxidative stress. However, few studies investigate the mechanisms of action of oxidised molecules in the regulation of immune cells. Thus, authors often assume that these events, sometime leading to oxidative stress, are conserved among species. The aim of this review is to draw the state-of-the-art of the current knowledge about the role of oxidised molecules and dietary antioxidant compounds in the regulation of the immune cell functions and suggest some perspectives for future investigations in animals of veterinary interest.
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页数:19
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