Effects of Grape Seed Proanthocyanidin Extract on Obesity

被引：61
作者：
Liu, Miao [1 ]
Yun, Peng [2 ]
Hu, Ying [1 ]
Yang, Jiao [1 ]
Khadka, Rim Bahadur [3 ]
Peng, Xiaochun [1 ]
机构：
[1] Yangtze Univ, Med Sch, Jingzhou, Peoples R China
[2] Sun Yat Sen Univ, Affiliated Hosp 7, Dept Endocrinol, Shenzhen, Peoples R China
[3] Yangtze Univ, Jingzhou, Peoples R China
来源：
OBESITY FACTS | 2020年 / 13卷 / 02期
关键词：
Grape seed proanthocyanidin extract; Obesity; Mechanism; DIET-INDUCED OBESITY; HIGH-FAT DIET; BROWN ADIPOSE-TISSUE; ENERGY-BALANCE; INSULIN-RESISTANCE; OXIDATIVE STRESS; GENE-EXPRESSION; MIR-122; LEVELS; MESSENGER-RNA; LIVER MIR-33A;
D O I：
10.1159/000502235
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Obesity is a chronic metabolic disease resulting from excessive fat accumulation and/or abnormal distribution caused by multiple factors. As a major component of metabolic syndrome, obesity is closely related to many diseases such as type 2 diabetes mellitus, hyperlipidemia, hypertension, coronary heart disease, stroke and cancer. Hence, the problem of obesity cannot be ignored, and recent studies have shown that grape seed proanthocyanidin extract (GSPE) has an antiobesity effect. This paper systematically reviews the research progress and potential mechanism of GSPE emphasizing on obesity prevention and treatment.
引用
收藏
页码：279 / 291
页数：13
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