An Assessment of New Sperm Tests for Male Infertility

被引:21
作者
Natali, Alessandro
Turek, Paul J.
机构
[1] Univ Florence, Urol Clin, Florence, Italy
[2] Turek Clin, San Francisco, CA USA
关键词
IN-VITRO FERTILIZATION; HYALURONIC-ACID BINDING; ASSAY SCSA PARAMETERS; HUMAN-SPERMATOZOA; CHROMATIN-STRUCTURE; SEMEN PARAMETERS; PREDICTIVE-VALUE; PREGNANCY RATES; DNA INTEGRITY; HEMIZONA ASSAY;
D O I
10.1016/j.urology.2010.10.005
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The routine semen analysis, although used for more than 50 years, fails to accurately distinguish between fertile and infertile men. As a consequence, many tests of sperm function (TSF) have been developed. This review discusses both older and newer diagnostic TSF. It outlines the principles underlying each assay and reviews aggregate clinical data to determine its current relevance and utility. It concludes that the relevance of many older TSF is questionable, with the wide acceptance of intracytoplasmic sperm injection (ICSI). Newer TSF have the potential to deliver more clinically relevant information but require more extensive study to better understand their predictive role in the ICSI era. UROLOGY 77: 1027-1034, 2011. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:1027 / 1034
页数:8
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