An Assessment of New Sperm Tests for Male Infertility

被引:21
作者
Natali, Alessandro
Turek, Paul J.
机构
[1] Univ Florence, Urol Clin, Florence, Italy
[2] Turek Clin, San Francisco, CA USA
关键词
IN-VITRO FERTILIZATION; HYALURONIC-ACID BINDING; ASSAY SCSA PARAMETERS; HUMAN-SPERMATOZOA; CHROMATIN-STRUCTURE; SEMEN PARAMETERS; PREDICTIVE-VALUE; PREGNANCY RATES; DNA INTEGRITY; HEMIZONA ASSAY;
D O I
10.1016/j.urology.2010.10.005
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The routine semen analysis, although used for more than 50 years, fails to accurately distinguish between fertile and infertile men. As a consequence, many tests of sperm function (TSF) have been developed. This review discusses both older and newer diagnostic TSF. It outlines the principles underlying each assay and reviews aggregate clinical data to determine its current relevance and utility. It concludes that the relevance of many older TSF is questionable, with the wide acceptance of intracytoplasmic sperm injection (ICSI). Newer TSF have the potential to deliver more clinically relevant information but require more extensive study to better understand their predictive role in the ICSI era. UROLOGY 77: 1027-1034, 2011. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:1027 / 1034
页数:8
相关论文
共 56 条
[1]  
Aitken RJ, 2006, INT J ANDROL, V29, P69, DOI 10.1111/j.1365-2605.2005.00630.x
[2]   Novel assay for determining DNA organization in human spermatozoa: Implications for male factor infertility [J].
Ankem, MK ;
Mayer, E ;
Ward, WS ;
Cummings, KB ;
Barone, JG .
UROLOGY, 2002, 59 (04) :575-578
[3]   Sperm protamine 1/protamine 2 ratios are related to in vitro fertilization pregnancy rates and predictive of fertilization ability [J].
Aoki, Vincent W. ;
Liu, Lihua ;
Jones, Kirtly P. ;
Hatasaka, Harry H. ;
Gibson, Mark ;
Peterson, C. Matthew ;
Carrell, Douglas T. .
FERTILITY AND STERILITY, 2006, 86 (05) :1408-1415
[4]   Predictive value of the hemizona assay for pregnancy outcome in patients undergoing controlled ovarian hyperstimulation with intrauterine insemination [J].
Arslan, Murat ;
Morshedi, Mahmood ;
Arslan, Ebru Ozturk ;
Taylor, Steve ;
Kanik, Arzu ;
Duran, Hakan E. ;
Oehninger, Sergio .
FERTILITY AND STERILITY, 2006, 85 (06) :1697-1707
[5]   Development of normal reference values for seminal reactive oxygen species and their correlation with leukocytes and semen parameters in a fertile population [J].
Athayde, Kelly S. ;
Cocuzza, Marcello ;
Agarwal, Ashok ;
Krajcir, Natalie ;
Lucon, Antonio M. ;
Srougi, Miguel ;
Hallak, Jorge .
JOURNAL OF ANDROLOGY, 2007, 28 (04) :613-620
[6]   ANILINE BLUE STAINING AS A MARKER OF SPERM CHROMATIN DEFECTS ASSOCIATED WITH DIFFERENT SEMEN CHARACTERISTICS DISCRIMINATES BETWEEN PROVEN FERTILE AND SUSPECTED INFERTILE MEN [J].
AUGER, J ;
MESBAH, M ;
HUBER, C ;
DADOUNE, JP .
INTERNATIONAL JOURNAL OF ANDROLOGY, 1990, 13 (06) :452-462
[7]   Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection [J].
Bartoov, B ;
Berkovitz, A ;
Eltes, F ;
Kogosovsky, A ;
Yagoda, A ;
Lederman, H ;
Artzi, S ;
Gross, M ;
Barak, Y .
FERTILITY AND STERILITY, 2003, 80 (06) :1413-1419
[8]   Selection of spermatozoa with normal nuclei to improve the pregnancy rate with intracytoplasmic sperm injection [J].
Bartoov, B ;
Berkovitz, A ;
Eltes, F .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (14) :1067-1068
[9]   Comparison between the toluidine blue stain and the Feulgen reaction for evaluation of rabbit sperm chromatin condensation and their relationship with sperm morphology [J].
Beletti, ME ;
Mello, MLS .
THERIOGENOLOGY, 2004, 62 (3-4) :398-402
[10]   The morphological normalcy of the sperm nucleus and pregnancy rate of intracytoplasmic injection with morphologically selected sperm [J].
Berkovitz, A ;
Eltes, F ;
Yaari, S ;
Katz, N ;
Barr, I ;
Fishman, A ;
Bartoov, B .
HUMAN REPRODUCTION, 2005, 20 (01) :185-190