Individualization of dose and fractionation of radiotherapy for head and neck cancers

被引：0

作者：

Blanchard, P. ^{[1
,2
,3
]}

Biau, J. ^{[4
,5
,6
]}

Castelli, J. ^{[7
,8
,9
]}

Tao, Y. ^{[1
]}

Graff, P. ^{[10
]}

Nguyen, F. ^{[1
]}

机构：

[1] Gustave Roussy, Dept Radiotherapie Oncol, Canc Campus,114 Rue Edouard Vaillant, F-94800 Villejuif, France

[2] CESP, INSERM, U1018, F-94800 Villejuif, France

[3] Univ Paris Saclay, F-94800 Villejuif, France

[4] Ctr Jean Perrin, Dept Radiotherapie Oncol, F-63000 Clermont Ferrand, France

[5] Univ Clermont Auvergne, F-63000 Clermont Ferrand, France

[6] INSERM, Imagerie Mol & Strat Theranost U1240, F-63000 Clermont Ferrand, France

[7] Ctr Eugene Marquis, Dept Radiotherapie, F-35000 Rennes, France

[8] INSERM, LTSI U1099, F-35000 Rennes, France

[9] Univ Rennes 1, F-35000 Rennes, France

[10] IUCT Oncopole, Dept Radiotherapie, F-31000 Toulouse, France

来源：

CANCER RADIOTHERAPIE | 2019年 / 23卷 / 6-7期

关键词：

Head and neck cancer; Nasopharyngeal cancer; Chemotherapy; Epstein-Barr virus; Meta-analysis; Radiotherapy; Fractionation; SQUAMOUS-CELL CARCINOMA; LOCALLY ADVANCED HEAD; TARGET VOLUMES CTV; HUMAN-PAPILLOMAVIRUS; RANDOMIZED-TRIAL; CONVENTIONAL RADIOTHERAPY; OROPHARYNGEAL CANCER; RADIATION-THERAPY; QUALITY-ASSURANCE; DE-ESCALATION;

D O I：

10.1016/j.canrad.2019.07.131

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Head and neck cancers comprise a variety of tumours depending on the sub-site, for which target volumes and the prescribed doses need to be individualized according to each patient's history and presentation. This article aims at describing the main factors involved in decision-making regarding dose and volume, as well as ongoing research. Contouring and treatment guidelines, use of altered fractionation, major prognostic factors, the role of Human papillomavirus and of functional imaging will be presented and discussed. (C) 2019 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.

引用

页码：784 / 788

页数：5

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