Aromatase inhibitors for breast cancer

被引:16
作者
Briest, Susanne
Davidson, Nancy E. [1 ]
机构
[1] Johns Hopkins Sidney Kimmel Ctr Comprehens Canc, Baltimore, MD USA
[2] Univ Leipzig, Dept Gynecol & Obstet, Leipzig, Germany
关键词
breast cancer; endocrine treatment; estrogen receptor; aromatase inhibitor; postmenopausal; hormonal therapy;
D O I
10.1007/s11154-007-9039-z
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Endocrine therapy is a mainstay for the many women who develop in situ or invasive steroid receptor-positive breast cancer. The use of tamoxifen has reduced mortality in such women. Recently estrogen deprivation strategies have come under scrutiny. Here the use of aromatase inhibitors for treatment of postmenopausal endocrine-responsive breast cancer in the metastatic, adjuvant, and preoperative settings is reviewed.
引用
收藏
页码:215 / 228
页数:14
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