Antithrombotic Therapy in Elderly Patients with Acute Coronary Syndromes

被引：7

作者：

Bonanad, Clara ^{[1
,2
,3
]}

Esteve-Claramunt, Francisca ^{[4
]}

Garcia-Blas, Sergio ^{[1
,2
,5
]}

Ayesta, Ana ^{[6
]}

Diez-Villanueva, Pablo ^{[7
]}

Perez-Rivera, Jose-Angel ^{[8
]}

Ferreiro, Jose Luis ^{[5
,9
]}

Canoves, Joaquim ^{[1
,2
,3
]}

Lopez-Fornas, Francisco ^{[1
,2
,3
]}

Ariza Sole, Albert ^{[8
]}

Raposerias, Sergio ^{[10
]}

Vivas, David ^{[11
]}

Blanco, Regina ^{[12
]}

Bompart Berroteran, Daznia ^{[3
]}

Cordero, Alberto ^{[5
,13
]}

Nunez, Julio ^{[1
,2
,3
,5
]}

Facila, Lorenzo ^{[14
]}

Nunez-Gil, Ivan J. ^{[11
]}

Gorriz, Jose Luis ^{[2
,3
,15
]}

Bodi, Vicente ^{[1
,2
,3
,5
]}

Martinez-Selles, Manuel ^{[16
]}

Ruiz Nodar, Juan Miguel ^{[17
]}

Chorro, Francisco Javier ^{[1
,2
,3
,5
]}

机构：

[1] Clin Univ Hosp Valencia, Cardiol Dept, Valencia 46010, Spain

[2] INCLIVA Biomed Res Inst, Valencia 46010, Spain

[3] Univ Valencia, Dept Med, Valencia 46010, Spain

[4] European Univ Valencia, Fac Hlth Sci, Dept Nursing, Valencia 46010, Spain

[5] Ctr Invest Biomed Red Enfermedades Cardiovasc CIB, Madrid 28029, Spain

[6] Cent Univ Hosp Asturias, Cardiol Dept, Oviedo 33011, Spain

[7] La Princesa Univ Hosp, Cardiol Dept, Madrid 28006, Spain

[8] Isabel I Univ, Univ Hosp Burgos, Cardiol Dept, Burgos 09003, Spain

[9] Bellvitge Univ Hosp, Cardiol Dept, Barcelona 08907, Spain

[10] Alvaro Cunqueiro Univ Hosp, Cardiol Dept, Vigo 36213, Spain

[11] Univ Complutense Madrid, San Carlos Univ Hosp, Cardiovasc Inst, Dept Med, Madrid 28040, Spain

[12] Quironsalud Hosp Valencia, Cardiol Dept, Valencia 46010, Spain

[13] San Juan Univ Hosp, Cardiol Dept, Alicante 00921, Spain

[14] Gen Univ Hosp Valencia, Cardiol Dept, Valencia 46014, Spain

[15] Clin Univ Hosp Valencia, Dept Nephrol, Valencia 46010, Spain

[16] Univ Complutense Madrid, Univ Europea, Hosp Univ Gregorio Maranon, Cardiol Dept, Madrid 28040, Spain

[17] Hosp Gen Univ Alicante, Inst Invest Sanitaria & Biomed Alicante ISABIAL, CIBER CV, Serv Cardiol, Alicante 03010, Spain

来源：

JOURNAL OF CLINICAL MEDICINE | 2022年 / 11卷 / 11期

关键词：

acute coronary syndrome; elderly; antiplatelet therapy; clopidogrel; prasugrel; ticagrelor; DUAL ANTIPLATELET THERAPY; NONVALVULAR ATRIAL-FIBRILLATION; PRECISE-DAPT SCORE; ORAL ANTICOAGULANTS; MYOCARDIAL-INFARCTION; PLATELET INHIBITION; STENT IMPLANTATION; OPEN-LABEL; CLOPIDOGREL; TICAGRELOR;

D O I：

10.3390/jcm11113008

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The treatment of acute coronary syndrome (ACS) in elderly patients continues to be a challenge because of the characteS.G.B.ristics of this population and the lack of data and specific recommendations. This review summarizes the current evidence about critical points of oral antithrombotic therapy in elderly patients. To this end, we discuss the peculiarities and differences reported referring to dual antiplatelet therapy (DAPT) in ACS management in elderly patients and what might be the best option considering these population characteristics. Furthermore, we analyze antithrombotic strategies in patients with atrial fibrillation (AF), with a particular focus on those cases that also present coronary artery disease (CAD). It is imperative to deepen our knowledge regarding the management of these challenging patients through real-world data and specifically designed geriatric studies to help resolve the questions remaining in their disease management.

引用

页数：15

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