Toxoplasma gondii infection: seroprevalence and associated risk factors for women of childbearing age in Osun State, Nigeria

被引:4
作者
Olarinde, Olaniran [1 ]
Sowemimo, Oluyomi A. [2 ]
Chuang, Ting-Wu [3 ,4 ,5 ,6 ]
Chou, Chia-Mei [3 ]
Olasanmi, Segun O. [7 ]
Ikotun, Kemisola [2 ]
Akinwale, Olaoluwa P. [8 ]
Gyang, Vincent P. [8 ]
Nwafor, Timothy [8 ]
Olukosi, Adeola Y. [9 ]
Chang, Jer-Hwa [10 ,11 ,12 ]
Fan, Chia-Kwung [3 ,4 ,5 ,6 ,13 ]
机构
[1] Obafemi Awolowo Univ, Coll Hlth Sci, Dept Microbiol & Parasitol, Ife, Osun State, Nigeria
[2] Obafemi Awolowo Univ, Fac Sci, Dept Zool, Ife, Osun State, Nigeria
[3] Taipei Med Univ, Coll Med, Sch Med, Dept Mol Parasitol & Trop Dis, Taipei, Taiwan
[4] Taipei Med Univ, Coll Med, Int PhD Program Med, Taipei, Taiwan
[5] Taipei Med Univ, Coll Med, Grad Inst Med Sci, Taipei, Taiwan
[6] Taipei Med Univ, Coll Med, Res Ctr Int Trop Med, Taipei, Taiwan
[7] Nigerian Inst Med Res, Dept Publ Hlth, Mol Parasitol Res Lab, Yaba, Nigeria
[8] Obafemi Awolowo Univ, Hlth Ctr & Med Serv, Ife, Osun State, Nigeria
[9] Nigerian Inst Med Res, Dept Biochem & Nutr, Yaba, Lagos State, Nigeria
[10] Taipei Med Univ, Coll Med, Sch Resp Therapy, Taipei, Taiwan
[11] Taipei Med Univ, Wan Fang Hosp, Dept Internal Med, Div Pulm Med, Taipei, Taiwan
[12] Taipei Med Univ, Wan Fang Hosp, Pulm Res Ctr, Taipei, Taiwan
[13] Taipei Med Univ, Wan Fang Hosp, Cell Physiol & Mol Image Res Ctr, Taipei, Taiwan
关键词
Toxoplasma gondii; seroprevalence; ELISA; risk factors; women of childbearing age; Osun State; Nigeria; PREGNANT-WOMEN; SEROCONVERSION; PREVALENCE;
D O I
10.1080/20477724.2021.1949193
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Toxoplasmosis is a common parasitic infection caused by an obligate intracellular protozoan, Toxoplasma gondii. Prevalence and risk factors of T. gondii infection in women of childbearing age in Osun State, Nigeria are unknown. This study was aimed to determine the seroprevalence and potential risk factors in acquiring T. gondii infection by women of childbearing age in Osun State, Nigeria. A community-based cross-sectional study was conducted from May 2019 to December 2019 in childbearing age women. Sera of 415 women aged 18-49 years randomly selected were collected and analyzed by enzyme-linked immunosorbent assay (ELISA) test. A questionnaire survey was administered for all study participants to collect socio-demographic and risk factors data. The study revealed that the overall seroprevalence of T. gondii infection was 76.63%, which comprised 6.02% positivity for anti-T. gondii IgM (25/415), 44.10% for IgG (183/415) and 26.51% for IgG plus IgM (110/415). Seroprevalence of IgM antibodies to T. gondii (6.02%) suggested recent infections. Women residing in rural communities and women of Islam religion showed significant association with anti-T. gondii seropositivity (p < 0.05). Residence location and women who are of Islam religion are risk factors to acquire T. gondii infection. Hence, health education and awareness on the disease and its transmission to women of childbearing age group in general and pregnant women in particular should be created during antenatal follow up to reduce the risk of T. gondii infection in pregnant women.
引用
收藏
页码:59 / 65
页数:7
相关论文
共 39 条
[1]  
Aguirre AA, 2019, ECOHEALTH, V16, P378, DOI 10.1007/s10393-019-01405-7
[2]  
[Anonymous], 2016, Infectious Diseases of the Fetus and Newborn Infant
[3]  
Avelino Mariza Martins, 2004, Braz J Infect Dis, V8, P164
[4]  
Dubey J.P., 1988, P1
[5]   Toxoplasma gondii infection: relationship between seroprevalence and risk factors among primary schoolchildren in the capital areas of Democratic Republic of Sao Tome and Principe, West Africa [J].
Fan, Chia-Kwung ;
Lee, Lin-Wen ;
Liao, Chien-Wei ;
Huang, Ying-Chieh ;
Lee, Yueh-Lun ;
Chang, Yu-Tai ;
Ramos Jose da Costa, Angela dos Santos ;
Gil, Vilfrido ;
Chi, Li-Hsing ;
Nara, Takeshi ;
Tsubouchi, Akiko ;
Akinwale, Olaoluwa Pheabian .
PARASITES & VECTORS, 2012, 5
[6]   Toxoplasma gondii in women of childbearing age and during pregnancy: seroprevalence study in Central and Southern Italy from 2013 to 2017 [J].
Fanigliulo, Daniela ;
Marchi, Serena ;
Montomoli, Emanuele ;
Trombetta, Claudia Maria .
PARASITE, 2020, 27
[7]   Toxoplasma Seroconversion with Negative or Transient Immunoglobulin M in Pregnant Women: Myth or Reality? A French Multicenter Retrospective Study [J].
Fricker-Hidalgo, H. ;
Cimon, B. ;
Chemla, C. ;
Darde, M. L. ;
Delhaes, L. ;
L'Ollivier, C. ;
Godineau, N. ;
Houze, S. ;
Paris, L. ;
Quinio, D. ;
Robert-Gangneux, F. ;
Villard, O. ;
Villena, I. ;
Candolfi, E. ;
Pelloux, H. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2013, 51 (07) :2103-2111
[8]   Seroepidemiology of Toxoplasma gondii infection in women of child-bearing age in central Ethiopia [J].
Gebremedhin, Endrias Zewdu ;
Abebe, Anteneh Hailu ;
Tessema, Tesfaye Sisay ;
Tullu, Kassu Desta ;
Medhin, Girmay ;
Vitale, Maria ;
Di Marco, Vincenzo ;
Cox, Eric ;
Dorny, Pierre .
BMC INFECTIOUS DISEASES, 2013, 13
[9]   Seroprevalence, Seroconversion, and Risk Factors for Toxoplasmosis among Pregnant Women in Taipei, Taiwan [J].
Hung, Ching-Sheng ;
Su, Hung-Wen ;
Lee, Yu-Luen ;
Weng, Hui-Wen ;
Wang, Yin-Chin ;
Naito, Toshio ;
Tsubouchi, Akiko ;
Wang, Giueng-Chueng ;
Fan, Chia-Kwung .
JAPANESE JOURNAL OF INFECTIOUS DISEASES, 2015, 68 (04) :312-317
[10]   Seroprevalence of human infection with Toxoplasma gondii and the associated risk factors, in Maiduguri, Borno state, Nigeria [J].
Kamani, J. ;
Mani, A. U. ;
Egwu, G. O. ;
Kumshe, H. A. .
ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 2009, 103 (04) :317-321