Emerging translational research on magnetic nanoparticles for regenerative medicine

被引:90
作者
Gao, Yu [1 ]
Lim, Jing [1 ]
Teoh, Swee-Hin [1 ]
Xu, Chenjie [1 ]
机构
[1] Nanyang Technol Univ, Sch Chem & Biomed Engn, Div Bioengn, Singapore 639798, Singapore
关键词
MESENCHYMAL STEM-CELLS; IRON-OXIDE NANOPARTICLES; BONE MORPHOGENETIC PROTEIN-2; OFF-LABEL USE; DRUG-DELIVERY; SUPERPARAMAGNETIC NANOPARTICLES; OSTEOGENIC DIFFERENTIATION; MECHANICAL COMPRESSION; CONTROLLED-RELEASE; TARGETED DELIVERY;
D O I
10.1039/c4cs00322e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Regenerative medicine, which replaces or regenerates human cells, tissues or organs, to restore or establish normal function, is one of the fastest-evolving interdisciplinary fields in healthcare. Over 200 regenerative medicine products, including cell-based therapies, tissue-engineered biomaterials, scaffolds and implantable devices, have been used in clinical development for diseases such as diabetes and inflammatory and immune diseases. To facilitate the translation of regenerative medicine from research to clinic, nanotechnology, especially magnetic nanoparticles have attracted extensive attention due to their unique optical, electrical, and magnetic properties and specific dimensions. In this review paper, we intend to summarize current advances, challenges, and future opportunities of magnetic nanoparticles for regenerative medicine.
引用
收藏
页码:6306 / 6329
页数:24
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