Geometrical considerations for the design of liquid-phase biochemical sensors using a cantilever's fundamental in-plane mode

被引:23
作者
Beardslee, L. A. [1 ]
Josse, F. [2 ]
Heinrich, S. M. [3 ]
Dufour, I. [4 ]
Brand, O. [1 ]
机构
[1] Georgia Inst Technol, Dept Elect & Comp Engn, Elect & Comp Engn Fac, Atlanta, GA 30332 USA
[2] Marquette Univ, Dept Elect & Comp Engn, Milwaukee, WI 53233 USA
[3] Marquette Univ, Dept Civil & Environm Engn, Milwaukee, WI 53233 USA
[4] Univ Bordeaux, IMS, Talence, France
基金
美国国家科学基金会;
关键词
Liquid-phase; Cantilevers; Bio-chemical sensors; MICROCANTILEVERS; ENVIRONMENT; INTEGRATION; SYSTEMS; CHIP;
D O I
10.1016/j.snb.2012.01.035
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The influence of the beam geometry on the quality factor and resonance frequency of resonant silicon cantilever beams vibrating in their fundamental in-plane flexural mode in water has been investigated. Compared to cantilevers vibrating in their first out-of-plane flexural mode, utilizing the in-plane mode results in reduced damping and reduced mass loading by the surrounding fluid. Quality factors as high as 86 have been measured in water for cantilevers with a 20 mu m thick silicon layer. Based on the experimental data, design guidelines are established for beam dimensions that ensure maximal Q-factors and minimal mass loading by the surrounding fluid, thus improving the limit-of-detection of mass-sensitive biochemical sensors. Elementary theory is also presented to help explain the observed trends. Additional discussion focuses on the tradeoffs that exist in designing liquid-phase biochemical sensors using in-plane cantilevers. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:7 / 14
页数:8
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