Hypoparathyroidism in the Adult: Epidemiology, Diagnosis, Pathophysiology, Target-Organ Involvement, Treatment, and Challenges for Future Research

被引：375
作者：
Bilezikian, John P. [1 ]
Khan, Aliya [2 ,3 ]
Potts, John T., Jr. [4 ,5 ]
Brandi, Maria Luisa [6 ]
Clarke, Bart L. [7 ]
Shoback, Dolores [8 ]
Jueppner, Harald [4 ,5 ,9 ]
D'Amour, Pierre [10 ,11 ]
Fox, John [12 ]
Rejnmark, Lars [13 ]
Mosekilde, Leif [13 ]
Rubin, Mishaela R. [1 ]
Dempster, David [14 ,15 ]
Gafni, Rachel [16 ]
Collins, Michael T. [16 ]
Sliney, Jim [1 ]
Sanders, James [17 ]
机构：
[1] Columbia Univ, Coll Phys & Surg, Dept Med, New York, NY 10032 USA
[2] McMaster Univ, Div Endocrinol, Hamilton, ON, Canada
[3] McMaster Univ, Div Geriatr, Hamilton, ON, Canada
[4] Massachusetts Gen Hosp, Endocrine Unit, Boston, MA 02114 USA
[5] Harvard Univ, Sch Med, Boston, MA USA
[6] Univ Florence, Sch Med, Dept Internal Med, Unit Bone & Mineral Metab, Florence, Italy
[7] Mayo Clin, Dept Med, Rochester, MN USA
[8] Univ Calif San Francisco, San Francisco VA Med Ctr, Endocrine Res Unit, San Francisco, CA 94143 USA
[9] Massachusetts Gen Hosp, Pediat Nephrol Unit, Boston, MA 02114 USA
[10] Hop St Luc, CHUM, Ctr Rech, Montreal, PQ H2X 1P1, Canada
[11] Univ Montreal, Dept Med, Montreal, PQ H3C 3J7, Canada
[12] NPS Pharmaceut, Bedminster, NJ USA
[13] Aarhus Univ Hosp, Dept Endocrinol & Internal Med, DK-8000 Aarhus, Denmark
[14] Helen Hayes Hosp, Reg Bone Ctr, W Haverstraw, NY USA
[15] Columbia Univ, Coll Phys & Surg, Dept Pathol, New York, NY 10032 USA
[16] Natl Inst Dent & Craniofacial Res, Craniofacial & Skeletal Dis Branch, NIH, Dept Hlth & Human Serv, Bethesda, MD USA
[17] Hypoparathyroidism Assoc, Idaho Falls, ID USA
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2011年 / 26卷 / 10期
关键词：
HYPOPARATHYROIDISM; CALCIUM; EPIDEMIOLOGY; GENETICS; PARATHYROID HORMONE; HYPOCALCEMIA; CALCIUM-SENSING RECEPTOR; PARATHYROID-HORMONE PTH; CANDIDIASIS-ECTODERMAL DYSTROPHY; BONE-MINERAL DENSITY; LONG-TERM TREATMENT; FAMILIAL ISOLATED HYPOPARATHYROIDISM; AUTOSOMAL-DOMINANT FORM; VITAMIN-D; POSTOPERATIVE HYPOPARATHYROIDISM; IDIOPATHIC HYPOPARATHYROIDISM;
D O I：
10.1002/jbmr.483
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Recent advances in understanding the epidemiology, genetics, diagnosis, clinical presentations, skeletal involvement, and therapeutic approaches to hypoparathyroidism led to the First International Workshop on Hypoparathyroidism that was held in 2009. At this conference, a group of experts convened to discuss these issues with a view towards a future research agenda for this disease. This review, which focuses primarily on hypoparathyroidism in the adult, provides a comprehensive summary of the latest information on this disease. (C) 2011 American Society for Bone and Mineral Research.
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收藏
页码：2317 / 2337
页数：21
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