Biological activity of galacto-oligosaccharides: A review

被引:45
作者
Mei, Zhaojun [1 ]
Yuan, Jiaqin [2 ]
Li, Dandan [3 ]
机构
[1] Luzhou Maternal & Child Hlth Hosp, Luzhou Peoples Hosp 2, Dept Pediat, Luzhou, Peoples R China
[2] Second Peoples Hosp Yibin, Dept Orthoped, Yibin, Peoples R China
[3] Univ Chinese Acad Sci, Beijing, Peoples R China
关键词
galacto-oligosaccharides; prebiotics; beta-galactosidase; biological activity; ulcerative colitis; INULIN-TYPE FRUCTANS; MIXTURE B-GOS; BETA-GALACTOSIDASE; DOUBLE-BLIND; BONE MINERALIZATION; CALCIUM-ABSORPTION; ULCERATIVE-COLITIS; COLORECTAL-CANCER; ATOPIC-DERMATITIS; GUT MICROBIOTA;
D O I
10.3389/fmicb.2022.993052
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Galacto-oligosaccharides (GOS) are oligosaccharides formed by beta-galactosidase transgalactosylation. GOS is an indigestible food component that can pass through the upper gastrointestinal tract relatively intact and ferment in the colon to produce short-chain fatty acids (SCFAs) that further regulate the body's intestinal flora. GOS and other prebiotics are increasingly recognized as useful food tools for regulating the balance of colonic microbiota-human health. GOS performed well compared to other oligosaccharides in regulating gut microbiota, body immunity, and food function. This review summarizes the sources, classification, preparation methods, and biological activities of GOS, focusing on the introduction and summary of the effects of GOS on ulcerative colitis (UC), to gain a comprehensive understanding of the application of GOS.
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页数:7
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