Bio-Inspired Enamel Repair via Glu-Directed Assembly of Apatite Nanoparticles: an Approach to Biomaterials with Optimal Characteristics

被引：115

作者：

Li, Li ^{[1
,2
]}

Mao, Caiyun ^{[4
]}

Wang, Jianming ^{[1
,2
]}

Xu, Xurong ^{[1
,2
,3
]}

Pan, Haihua ^{[1
,2
,3
]}

Deng, Yan ^{[5
]}

Gu, Xinhua ^{[4
]}

Tang, Ruikang ^{[1
,2
,3
]}

机构：

[1] Zhejiang Univ, Ctr Biopathways & Biomat, Hangzhou 310027, Zhejiang, Peoples R China

[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Zhejiang, Peoples R China

[3] Zhejiang Univ, State Key Lab Silicon Mat, Hangzhou 310027, Zhejiang, Peoples R China

[4] Zhejiang Univ, Affiliated Hosp 1, Coll Med, Hangzhou 310003, Zhejiang, Peoples R China

[5] Unilever Discover Shanghai, Shanghai 200233, Peoples R China

来源：

ADVANCED MATERIALS | 2011年 / 23卷 / 40期

基金：

中国国家自然科学基金;

关键词：

HYDROXYAPATITE NANOPARTICLES; CALCIUM-PHOSPHATE; MATRIX PROTEINS; DENTAL ENAMEL; AMINO-ACIDS; CRYSTALLIZATION; ORGANIZATION; ADSORPTION; AMELOGENIN; CRYSTALS;

D O I：

10.1002/adma.201102773

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A biomimetic construction of enamel-like apatite material is achieved by the cooperation of nanoparticles and Glu on enamel substrate under physiological conditions; the artificial apatite layer shares the exactly same crystallographic and tectonic properties with the natural enamel; and the apparent restoration of enamel hardness is particularly significant. We suggest a biomineralization-inspired strategy to approach biomaterials with optimal characteristics.

引用

页码：4695 / +

页数：8

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