An Overview of Synthesis and Biological Activity of Dihydropyrimidine Derivatives

被引：4

作者：

Dudhe, Anshu Chaudhary ^{[1
]}

Dudhe, Rupesh ^{[1
]}

Porwal, Omji ^{[2
]}

Katole, Gayatri ^{[1
]}

机构：

[1] GH Raisoni Univ, Sch Pharm, Chhindwara 480337, Madhya Pradesh, India

[2] Tishk Int Univ, Fac Pharm, Dept Pharm, Erbil, KRG, Iraq

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2022年 / 22卷 / 05期

关键词：

Dihydropyrimidine; bignelli reaction; anticancer; antimicrobial; antiviral; synthesis; IN-VITRO ANTICANCER; ANTIMICROBIAL EVALUATION; ANTIFUNGAL ACTIVITY; BIGINELLI REACTION; INHIBITORS; SILICO; ALPHA;

D O I：

10.2174/1389557521666210920120457

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Dihydropyrimidine derivatives are the most important scaffolds due to structural similarities with natural products; it is a heterocyclic compound. The chemistry of Dihydropyrimidine is a growing field. Various reaction schemes for the preparation of Dihydropyrimidines produce different biological effects and offer vast scope in the field of medicinal chemistry. This article's goal is to analyze the work that reported the recent chemistry and pharmacological activities of dihydropyrimidine derivatives.

引用

页码：701 / 728

页数：28

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