Synthesis and structures of tris(pyrazolyl)hydroborato metal complexes as structural model compounds of carbonicanhydrase

被引：25

作者：

Guo, SL

Ding, E

Yin, YQ ^{[1
]}

Yu, KB

机构：

[1] Acad Sinica, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China

[2] Acad Sinica, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China

来源：

POLYHEDRON | 1998年 / 17卷 / 22期

关键词：

tris(pyrazolyl)hydroborato; metal complexes; crystal structure;

D O I：

10.1016/S0277-5387(98)00139-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of tris(pyrazoly)hydroborato metal complexes [eta(3)-HB(3-R-1-5-R(2)pz)(3)]MX (R-1=Ph, 2'-thienyl, R-2=CH3, Ph; M=Ni, Cu, Zn, Cd; X=Cl-, NO3- CH3COO-) and [eta(3)-HB(3-Ph-5-Mep;)(3)](3-Me5-Phpz)Cu(PhCOO), 8, had been synthesized and characterized. Among them, the complexes [eta(3)-HB(3,5-Ph(2)pz)(3)]NiCl (3), [eta(3)-HB(3-Ph-5-Mepz)(3)]Cd(NO3)(THF) (4) and 8 were analyzed by X-ray crystal structure determination, which revealed the bidentate coordination of NO3- in complex 4 and isomerized ligands in complex 8. As model compounds of carbonic anhydrase (CA), the structures of these complexes were contrasted to that of the active site of CA: the derivative chloro may be the closest model compounds among them. The relationship between the coordination modes of X (X = NO3- CH3COO-; PhCOO-) in complexes and their IR spectra was also discussed. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：3841 / 3849

页数：9

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