Recent Advances in Cyanobacterial Biotransformations

被引：6

作者：

Malihan-Yap, Lenny ^{[1
]}

Grimm, Hanna C. ^{[1
]}

Kourist, Robert ^{[1
,2
]}

机构：

[1] Graz Univ Technol, Inst Mol Biotechnol, NAWI Graz, A-8010 Graz, Austria

[2] ACIB GmbH, A-8010 Graz, Austria

来源：

CHEMIE INGENIEUR TECHNIK | 2022年 / 94卷 / 11期

关键词：

Biocatalysis; Biotransformations; Cyanobacteria; Photosynthesis; ASYMMETRIC REDUCTION; PCC; 6803; INDUSTRIAL BIOTECHNOLOGY; HYDROGEN PHOTOPRODUCTION; HEAVY-METAL; LIGHT; PHOTOSYNTHESIS; BIOCATALYSIS; OXIDATION; WATER;

D O I：

10.1002/cite.202200077

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Light-driven biotransformations in recombinant cyanobacteria have been explored in recent years for the production of chiral compounds and platform chemicals. In particular, cyanobacteria harboring oxidoreductases proved to be sustainable hosts providing and recycling reducing equivalents and improving the atom economy of the reactions. However, the provision of light in photobioreactors is considered to be the major bottleneck for up-scaling. In this review, genetic tools for generating recombinant cyanobacterial strains and up to date cyanobacterial biotransformations including redesigning of the photosynthetic electron transport chain to increase specific activities are presented. Finally, several photobioreactor geometries to circumvent the light limitation are discussed and some future perspectives are presented.

引用

页码：1628 / 1644

页数：17

共 97 条

[1]

Al-Haj Lamya, 2016, Life-Basel, V6, P42, DOI 10.3390/life6040042

[2] Flavodiiron proteins Flv1 and Flv3 enable cyanobacterial growth and photosynthesis under fluctuating light [J].

Allahverdiyeva, Yagut ;

Mustila, Henna ;

Ermakova, Maria ;

Bersanini, Luca ;

Richaud, Pierre ;

Ajlani, Ghada ;

Battchikova, Natalia ;

Cournac, Laurent ;

Aro, Eva-Mari .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (10) :4111-4116

[3] Engineering of NADPH Supply Boosts Photosynthesis-Driven Biotransformations [J].

Assil-Companioni, Leen ;

Buchsenschutz, Hanna C. ;

Solymosi, Daniel ;

Dyczmons-Nowaczyk, Nina G. ;

Bauer, Kristin K. F. ;

Wallner, Silvia ;

Macheroux, Peter ;

Allahverdiyeva, Yagut ;

Nowaczyk, Marc M. ;

Kourist, Robert .

ACS CATALYSIS, 2020, 10 (20) :11864-11877

[4] Biotransformations of monoterpenes by photoautotrophic micro-organisms [J].

Balcerzak, L. ;

Lipok, J. ;

Strub, D. ;

Lochynski, S. .

JOURNAL OF APPLIED MICROBIOLOGY, 2014, 117 (06) :1523-1536

[5] Comparative Dose-Response Analysis of Inducible Promoters in Cyanobacteria [J].

Behle, Anna ;

Saake, Pia ;

Germann, Anna T. ;

Dienst, Dennis ;

Axmann, Ilka M. .

ACS SYNTHETIC BIOLOGY, 2020, 9 (04) :843-855

[6] Rational engineering of photosynthetic electron flux enhances light-powered cytochrome P450 activity [J].

Berepiki, Adokiye ;

Gittins, John R. ;

Moore, C. Mark ;

Bibby, Thomas S. .

SYNTHETIC BIOLOGY, 2018, 3 (01)

[7] Photoenzymes and Related Topics: An Update [J].

Bjoern, Lars Olof .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 2018, 94 (03) :459-465

[8] Characterization of Stress Responses of Heavy Metal and Metalloid Inducible Promoters in Synechocystis PCC6803 [J].

Blasi, Barbara ;

Peca, Loredana ;

Vass, Imre ;

Kos, Peter B. .

JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2012, 22 (02) :166-169

[9] Enzymatic Oxyfunctionalization Driven by Photosynthetic Water-Splitting in the Cyanobacterium Synechocystis sp PCC 6803 [J].

Boehmer, Stefanie ;

Koeninger, Katharina ;

Gomez-Baraibar, Alvaro ;

Bojarra, Samiro ;

Muegge, Carolin ;

Schmidt, Sandy ;

Nowaczyk, Marc M. ;

Kourist, Robert .

CATALYSTS, 2017, 7 (08)

[10] Evolutionary diverse Chlamydomonas reinhardtii Old Yellow Enzymes reveal distinctive catalytic properties and potential for whole-cell biotransformations [J].

Bohmer, Stefanie ;

Marx, Christina ;

Gomez-Baraibar, Alvaro ;

Nowaczyk, Marc M. ;

Tischler, Dirk ;

Hemschemeier, Anja ;

Happe, Thomas .

ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2020, 50

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