Catalytic asymmetric conjugate boration of α,β-unsaturated sulfones

被引：78

作者：

Moure, Abraham L. ^{[1
]}

Gomez Arrayas, Ramon ^{[1
]}

Carretero, Juan C. ^{[1
]}

机构：

[1] Univ Autonoma Madrid, Dept Quim Organ, E-28049 Madrid, Spain

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 23期

关键词：

BETA-KETO SULFONES; TERTIARY ORGANOBORONIC ESTERS; ENANTIOSELECTIVE SYNTHESIS; CARBONYL-COMPOUNDS; COUPLING REACTIONS; ADDITIONS; ENONES; BIS(PINACOLATO)DIBORON; CONFIGURATION; DERIVATIVES;

D O I：

10.1039/c1cc11949d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The alpha,beta-unsaturated sulfones are suitable activated olefins in catalytic asymmetric conjugate beta-boration. These substrates undergo smooth conjugate addition of bis(pinacolato) diboron [B(2)(pin)(2)] catalyzed by nonracemic Cu(I)-diphosphine complexes to provide, upon subsequent oxidation, beta-hydroxy sulfones in good yields and high enantiocontrol.

引用

页码：6701 / 6703

页数：3

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