Chemical constituents of Menispermum dauricum

被引：12
|
作者：
Chen Jian-Yong [1 ]
Xie Yu-Feng [2 ]
Zhou Tian-Xi [1 ]
Qin Guo-Wei [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
[2] Guangdong Coll Pharm, Guangzhou 510006, Guangdong, Peoples R China
来源：
CHINESE JOURNAL OF NATURAL MEDICINES | 2012年 / 10卷 / 04期
关键词：
Menispermum dauricum; Chlorine-containing alkaloids; Chemical constituents; ALKALOIDS;
D O I：
10.3724/SP.J.1009.2012.00292
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
AIM: To study the chemical constituents of Menispermum dauricum DC. METHODS: Compounds were isolated by repeated chromatography on silica gel and Sephadex LH-20. The structures were identified by spectral analysis and comparison with literature data. RESULTS: Eleven compounds were obtained and identified as dauricumine (1), dauricumidine (2), acutuminine (3), physcion (4), blumenol C (5), blumenolA (6), N-trans feruloyltyramine (7), vanillin (8), beta-sitostenone (9), beta-sitosterol (10), and daucosterol (11). CONCLUSION: All compounds were known, but isolated from the plant for first time. Compounds 1 and 2 were chlorine-containing alkaloids obtained from natural source for the first time. The stereochemistry of 3 was determined for first time.
引用
收藏
页码：292 / 294
页数：3
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