INTEGRATED MULTI-OMICS REVEAL INTRATUMOUR HETEROGENEITY AND NOVEL THERAPEUTIC TARGETS IN PAEDIATRIC EPENDYMOMA

被引:0
|
作者
Pandele, Alina [1 ]
Woodward, Alison [1 ]
Lankford, Sophie [1 ]
Macarthur, Donald [2 ]
Kamaly-Asl, Ian [3 ]
Barrett, David [4 ]
Grundy, Richard [1 ]
Kim, Dong-Hyun [4 ]
Rahman, Ruman [5 ]
机构
[1] Univ Nottingham, Biodiscovery Inst, Sch Med, Childrens Brain Tumour Res Ctr, Nottingham, England
[2] Nottingham Univ Hosp NHS Trust, Dept Neurosurg, Nottingham, England
[3] Royal Manchester Childrens Hosp, Manchester, Lancs, England
[4] Univ Nottingham, Sch Pharm, Ctr Analyt Biosci Adv Mat & Healthcare Technol, Nottingham, England
[5] Univ Nottingham, Biodiscovery Inst, Sch Med, Nottingham, England
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
TAMI-76
引用
收藏
页码:214 / 214
页数:1
相关论文
共 50 条
  • [41] Identifying prioritization of therapeutic targets for ankylosing spondylitis: a multi-omics Mendelian randomization study
    Dai, Lingyu
    Xia, Lan
    Su, Guannan
    Gao, Yu
    Jiang, Qingyan
    Yang, Peizeng
    JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 22 (01)
  • [42] The role of multi-omics in the diagnosis of COVID-19 and the prediction of new therapeutic targets
    Ma, Jianli
    Deng, Yuwei
    Zhang, Minghui
    Yu, Jinming
    VIRULENCE, 2022, 13 (01) : 1101 - 1110
  • [43] Integrated multi-omics analyses reveal the TM4SF family genes with prognostic and therapeutic relevance in hepatocellular carcinoma
    Tang, Qiang
    Wang, Shurui
    Li, Huimin
    Liu, Junzhi
    Hu, Xin
    Zhao, Dong
    Di, Maojun
    AGING-US, 2024, 16 (01): : 593 - 616
  • [44] Multi-omics analysis reveals the potential pathogenesis and therapeutic targets of diabetic kidney disease
    Wei, Lan
    Gao, Jingjing
    Wang, Liangzhi
    Tao, Qianru
    Tu, Chao
    HUMAN MOLECULAR GENETICS, 2024, 33 (02) : 122 - 137
  • [45] Application of Multi-Omics Approach in Sarcomas: A Tool for Studying Mechanism, Biomarkers, and Therapeutic Targets
    Zou, Zijian
    Sun, Wei
    Xu, Yu
    Liu, Wanlin
    Zhong, Jingqin
    Lin, Xinyi
    Chen, Yong
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [46] Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma
    Dimitrakopoulos, Christos
    Hindupur, Sravanth Kumar
    Colombi, Marco
    Liko, Dritan
    Ng, Charlotte K. Y.
    Piscuoglio, Salvatore
    Behr, Jonas
    Moore, Ariane L.
    Singer, Jochen
    Ruscheweyh, Hans-Joachim
    Matter, Matthias S.
    Mossmann, Dirk
    Terracciano, Luigi M.
    Hall, Michael N.
    Beerenwinkel, Niko
    BMC GENOMICS, 2021, 22 (01)
  • [47] Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma
    Christos Dimitrakopoulos
    Sravanth Kumar Hindupur
    Marco Colombi
    Dritan Liko
    Charlotte K. Y. Ng
    Salvatore Piscuoglio
    Jonas Behr
    Ariane L. Moore
    Jochen Singer
    Hans-Joachim Ruscheweyh
    Matthias S. Matter
    Dirk Mossmann
    Luigi M. Terracciano
    Michael N. Hall
    Niko Beerenwinkel
    BMC Genomics, 22
  • [48] Multi-omics approaches to therapeutic target identification
    Hassan, Md Imtaiyaz
    BRIEFINGS IN FUNCTIONAL GENOMICS, 2023, 22 (02) : 75 - 75
  • [49] i-Modern: Integrated multi-omics network model identifies potential therapeutic targets in glioma by deep learning with interpretability
    Pan, Xingxin
    Burgman, Brandon
    Wu, Erxi
    Huang, Jason H.
    Sahni, Nidhi
    Yi, S. Stephen
    COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2022, 20 : 3511 - 3521
  • [50] Integrated multi-omics analysis of Alzheimer’s disease shows molecular signatures associated with disease progression and potential therapeutic targets
    Pradeep Kodam
    R. Sai Swaroop
    Sai Sanwid Pradhan
    Venketesh Sivaramakrishnan
    Ramakrishna Vadrevu
    Scientific Reports, 13